"PKN2" Related Products

Expand

Recombinant Human Protein Kinase N2, GST-tagged, Active

Cat. No. : PKN2-411H
Product Overview : Recombinant full-length human PKN2 was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=145kDa.
Description : PKN2 (also known as PRK2) is a Rho effector and a member of the protein kinase C superfamily of serine/threonine kinases. PKN2 is an essential regulator of both entry into mitosis and exit from cytokinesis in HeLa S3 cells. PKN2 is required for abscission of the midbody at the end of the cell division cycle and for phosphorylation and activation of Cdc25B, the phosphatase required for activation of mitotic cyclin/Cdk1 complexes at the G2/M transition. C-terminus of PKN2 could be a potential drug target for effector-specific pharmacological intervention of Rho-medicated biological processes.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : PKN2 protein kinase N2 [ Homo sapiens ]
Synonyms : PKN2; protein kinase N2; PAK2; PRK2; Pak-2; PRKCL2; PRO2042; MGC71074; MGC150606; protein kinase C-like 2; cardiolipin-activated protein kinase Pak2; EC 2.7.11.13
Gene ID : 5586
mRNA Refseq : NM_006256
Protein Refseq : NP_006247
MIM : 602549
UniProt ID : Q16513
Chromosome Location : 1p22.2
Function : ATP binding; nucleotide binding; protein kinase C activity; transferase activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.