Recombinant Human TAO Kinase 2, GST-tagged, Active

• Cat.No.: TAOK2-442H
• Product Overview: Recombinant human TAOK2 (1-314) was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 63 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 1-314 a.a.
• Description: Thousand and one-amino acid protein kinase 2 (TAOK 2) is part of the stress-sensitive kinase cascade and activation of and binding to MKK3 by TAOK2 implicates it in the regulation of the p38-containing stress-responsive MAP kinase pathway. TAOK2 protein kinase activates p38 mitogen-activated protein kinase cascade in vitro and in cells by phosphorylating the MAP/ERK kinases MKK3 and MKK6. TAO2 may play an important role in the activation of specific intracellular signaling pathways that are unique to osmotic stress.
• Sequence: 1-314.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: TAOK2 TAO kinase 2 [ Homo sapiens ]
• Synonyms: TAOK2; TAO kinase 2; PSK; PSK1; TAO1; TAO2; MAP3K17; KIAA0881; prostate derived STE20-like kinase PSK; thousand and one amino acid protein kinase; EC 2.7.11.1; PSK-1; hKFC-C; Kinase from chicken homolog C; Prostate-derived STE20-like kinase 1; Thousand and one amino acid protein 2; prostate derived STE20-like kinase PSK; Serine/threonine-protein kinase TAO2
• Gene ID: 9344
• mRNA Refseq: NM_004783
• Protein Refseq: NP_004774
• UniProt ID: Q9UL54
• Chromosome Location: 16p11.2
• Pathway: MAPK signaling pathway
• Function: ATP binding; magnesium ion binding; nucleotide binding; protein serine/threonine kinase activity; transferase activity