"TAOK2" Related Products


Recombinant Human TAO Kinase 2, GST-tagged, Active

Cat. No. : TAOK2-442H
Product Overview : Recombinant human TAOK2 (1-314) was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 63 kDa.
Description : Thousand and one-amino acid protein kinase 2 (TAOK 2) is part of the stress-sensitive kinase cascade and activation of and binding to MKK3 by TAOK2 implicates it in the regulation of the p38-containing stress-responsive MAP kinase pathway. TAOK2 protein kinase activates p38 mitogen-activated protein kinase cascade in vitro and in cells by phosphorylating the MAP/ERK kinases MKK3 and MKK6. TAO2 may play an important role in the activation of specific intracellular signaling pathways that are unique to osmotic stress.
Source : Sf9 insect cells using baculovirus.
Sequence : 1-314.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDB rendering based on 1u5q. :

Gene Name : TAOK2 TAO kinase 2 [ Homo sapiens ]
Synonyms : TAOK2; TAO kinase 2; PSK; PSK1; TAO1; TAO2; MAP3K17; KIAA0881; prostate derived STE20-like kinase PSK; thousand and one amino acid protein kinase; EC; PSK-1; hKFC-C; Kinase from chicken homolog C; Prostate-derived STE20-like kinase 1; Thousand and one amino acid protein 2; prostate derived STE20-like kinase PSK; Serine/threonine-protein kinase TAO2
Gene ID : 9344
mRNA Refseq : NM_004783
Protein Refseq : NP_004774
UniProt ID : Q9UL54
Chromosome Location : 16p11.2
Pathway : MAPK signaling pathway
Function : ATP binding; magnesium ion binding; nucleotide binding; protein serine/threonine kinase activity; transferase activity

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