Recombinant Human TXK Tyrosine Kinase, GST-tagged, Active

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human TXK Tyrosine Kinase, GST-tagged, Active

Recombinant Human TXK Tyrosine Kinase, GST-tagged, Active

TXK Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : TXK-453H
Product Overview : Recombinant human TXK (239-end) was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag.MW = 53 kDa.
Description : TXK or RLK is a member of the TEC family of non-receptor tyrosine kinases. TXK is expressed in T-cells and is an important component of signaling pathways downstream of lymphocyte antigen receptor. TXK is phosphorylated in response to T-cell receptor stimulation and can be activated by phosphorylation by Src family kinases. However, TXK is phosphorylated independent of PI-3K activity.. Excessive TXK protein expression is seen in patients with Behcet"s disease. Over production of TXK leads to increased Th1 cell function that is involved in the pathogenesis of Behcet's disease.
Source : Sf9 insect cells using baculovirus.
Sequence : 239-end.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDB rendering based on 2dm0. :

Gene Name : TXK TXK tyrosine kinase [ Homo sapiens ]
Synonyms : TXK tyrosine kinase; RLK; TKL; BTKL; PTK4; PSCTK5; MGC22473; TXK; tyrosine kinase; PTK4 protein tyrosine kinase 4; EC 2.7.10.2
Gene ID : 7294
mRNA Refseq : NM_003328
Protein Refseq : NP_003319
MIM : 600058
UniProt ID : P42681
Chromosome Location : 4p12
Pathway : Leukocyte transendothelial migration
Function : non-membrane spanning protein tyrosine kinase activity; nucleotide binding; ATP binding; transferase activity; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry


  • Note: There will be extra charge for optional service!

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy