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Recombinant Human ADH1B

Cat.No. : ADH1B-26900TH
Product Overview : Recombinant full length Human ADH1B with N terminal proprietary tag. Predicted MW 66.99 kDa.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
Protein length : 375 amino acids
Molecular Weight : 66.990kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIK MVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEG VTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAK IDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFG LGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL LCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVY GGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF DLLHSGKSIRTVLTF
Sequence Similarities : Belongs to the zinc-containing alcohol dehydrogenase family.
Gene Name : ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide [ Homo sapiens ]
Official Symbol : ADH1B
Synonyms : ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide; ADH2; alcohol dehydrogenase 1B;
Gene ID : 125
mRNA Refseq : NM_000668
Protein Refseq : NP_000659
Uniprot ID : P00325
Chromosome Location : 4q23
Pathway : Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Ethanol oxidation, organism-specific biosystem; Fatty Acid Omega Oxidation, organism-specific biosystem;
Function : alcohol dehydrogenase activity, zinc-dependent; metal ion binding; nucleotide binding; oxidoreductase activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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