Recombinant Human AGRN, His-tagged
Cat.No. : | AGRN-26658TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 1601-2045 of Human Agrin with a N terminal His tag; 52kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitution with 127 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | APCRVLPEGGAQCECPLGREGTFCQ TASGQDGSGPFLADF NGFSHLELRGLHTFARDLGEKMALE VVFLARGPSGLLL YNGQKTDGKGDFVSLALRDRRLEFR YDLGKGAAVIRSR EPVTLGAWTRVSLERNGRKGALRVG DGPRVLGESPVPHTV LNLKEPLYVGGAPDFSKLARAAAVS SGFDGAIQLVSLG GRQLLTPEHVLRQVDVTSFAGHPCT RASGHPCLNGASC VPREAAYVCLCPGGFSGPHCEKGLV EKSAGDVDTLAFDGRTFVEYLNAVT ESEKALQSNHFELSLRTEATQGLVL WSG KATERADYVALAIVDGHLQLSYNLG SQPVVLRSTVPVN TNRWLRVVAHREQREGSLQVGNEAP VTGSSPLGATQLD TDGALWLGGLPELPVGPALPKAYGT GFVGCLRDVVVGRHP LHLLEDAVTKPELRPCPTP |
Gene Name : | AGRN agrin [ Homo sapiens ] |
Official Symbol : | AGRN |
Synonyms : | AGRN; agrin; AGRIN; agrin proteoglycan; |
Gene ID : | 375790 |
mRNA Refseq : | NM_198576 |
Protein Refseq : | NP_940978 |
MIM : | 103320 |
Uniprot ID : | O00468 |
Chromosome Location : | 1p36.33 |
Pathway : | Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; |
Function : | acetylcholine receptor regulator activity; laminin binding; protein binding; structural constituent of cytoskeleton; |
Products Types
◆ Recombinant Protein | ||
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AGRN-220R | Recombinant Rat AGRN Protein, His (Fc)-Avi-tagged | +Inquiry |
Agrn-6784R | Recombinant Rat Agrn protein, His & T7-tagged | +Inquiry |
AGRN-132H | Recombinant Human AGRN protein, His-tagged | +Inquiry |
AGRN-12H | Recombinant Human AGRN protein, His/T7-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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