"ARL6" Related Products

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Recombinant Human ARL6, His-tagged

Cat.No.: ARL6-26185TH
Product Overview: Recombinant full length Human ARL6 with an N terminal His tag; 206 amino acids with the tag; predicted MWt: 23.2 kDa.
Description: The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.
Protein length: 186 amino acids
Conjugation: HIS
Molecular Weight: 23.200kDa inclusive of tags
Source: E. coli
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH SGQGRYRNLW EHYYKEGQAI IFVIDSSDRL RMVVAKEELD TLLNHPDIKH RRIPILFFAN KMDLRDAVTS VKVSQLLCLE NIKDKPWHIC MGLLDRLSVL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQNILPT IGFSIEKFKS SSLSFTVFDM ASDAIKGEGL QEGVDWLQDQ IQTVKT
Sequence Similarities: Belongs to the small GTPase superfamily. Arf family.
Gene Name: ARL6 ADP-ribosylation factor-like 6 [ Homo sapiens ]
Official Symbol: ARL6
Synonyms: ARL6; ADP-ribosylation factor-like 6; BBS3; ADP-ribosylation factor-like protein 6;
Gene ID: 84100
mRNA Refseq: NM_177976
Protein Refseq: NP_816931
MIM: 608845
Uniprot ID: Q9H0F7
Chromosome Location: 3q11.2
Function: GTP binding; metal ion binding; nucleotide binding; phospholipid binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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