Recombinant Human C19ORF2
| Cat.No. : | C19ORF2-27164TH |
| Product Overview : | Recombinant full length human C19orf2 with proprietary tag; amino acids 1-535, approximately 86kDa. |
- Specification
- Gene Information
- Related Products
| Description : | The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Source : | E. coli |
| Form : | Liquid |
| Purity : | >95% by SDS-PAGE |
| Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0 |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Gene Name : | C19orf2 chromosome 19 open reading frame 2 [ Homo sapiens ] |
| Official Symbol : | C19ORF2 |
| Synonyms : | C19ORF2; chromosome 19 open reading frame 2; unconventional prefoldin RPB5 interactor; FLJ10575; NNX3; PPP1R19; protein phosphatase 1; regulatory subunit 19; RMP; RPB5 mediating protein; URI; |
| Gene ID : | 8725 |
| mRNA Refseq : | NM_134447 |
| Protein Refseq : | NP_604431 |
| MIM : | 603494 |
| Uniprot ID : | O94763 |
| Chromosome Location : | 19q12 |
| Function : | protein binding; transcription corepressor activity; unfolded protein binding; |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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