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Recombinant Human Calcium Binding Protein 39, GST-tagged

Cat.No. : CAB39-1471H
Product Overview : Recombinant full-length human MO25alpha was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 63kDa.
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Cat. No. : CAB39-1471H
Description : MO25α (mouse protein 25 alpha) is a 40-kDa protein that interacts with the STE20-related adaptor-alpha (STRADα) pseudo kinase to form a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. LKB1 plays a critical role in cell proliferation, polarity and energy metabolism. LKB1 is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). MO25α binds directly to a conserved Trp-Glu-Phe sequence at the STRADα C terminus, and markedly enhances the binding of STRADα to LKB1 thereby increasing LKB1.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : CAB39 calcium binding protein 39 [ Homo sapiens ]
Synonyms : CAB39; calcium binding protein 39; MO25; CGI-66; FLJ22682; Protein Mo25
Gene ID : 51719
mRNA Refseq : NM_001130849
Protein Refseq : NP_001124321
MIM : 612174
UniProt ID : Q9Y376
Chromosome Location : 2q37.1
Pathway : mTOR signaling pathway; Integration of energy metabolism
Function : protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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