Recombinant Human Calcium Binding Protein 39, GST-tagged CAB39-1471H

Recombinant Human Calcium Binding Protein 39, GST-tagged

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Recombinant Human Calcium Binding Protein 39, GST-tagged

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Cat. No. : CAB39-1471H
Product Overview : Recombinant full-length human MO25alpha was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 63kDa.
Description : MO25α (mouse protein 25 alpha) is a 40-kDa protein that interacts with the STE20-related adaptor-alpha (STRADα) pseudo kinase to form a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. LKB1 plays a critical role in cell proliferation, polarity and energy metabolism. LKB1 is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). MO25α binds directly to a conserved Trp-Glu-Phe sequence at the STRADα C terminus, and markedly enhances the binding of STRADα to LKB1 thereby increasing LKB1.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDB rendering based on 1upk. :

Gene Name : CAB39 calcium binding protein 39 [ Homo sapiens ]
Synonyms : CAB39; calcium binding protein 39; MO25; CGI-66; FLJ22682; Protein Mo25
Gene ID : 51719
mRNA Refseq : NM_001130849
Protein Refseq : NP_001124321
MIM : 612174
UniProt ID : Q9Y376
Chromosome Location : 2q37.1
Pathway : mTOR signaling pathway; Integration of energy metabolism
Function : protein binding

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