Recombinant Human CDC34, His-tagged CDC34-26224TH

Recombinant Human CDC34, His-tagged

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Recombinant Human CDC34, His-tagged

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Cat.No. : CDC34-26224TH
Product Overview : Recombinant full length Human Cdc34 with His tag, 32kDa.
Description : The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.
Protein length : 236 amino acids
Conjugation : HIS
Molecular Weight : 32.000kDa inclusive of tags
Source : E. coli
Tissue specificity : Expressed in testes during spermatogenesis to regulate repression of cAMP-induced transcription.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : pH: 8.00Constituents:1.2% HEPES, 0.292% Sodium chloride, 0.02% DTT
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the ubiquitin-conjugating enzyme family.
Gene Name : CDC34 cell division cycle 34 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : CDC34
Synonyms : CDC34; cell division cycle 34 homolog (S. cerevisiae); cell division cycle 34; ubiquitin-conjugating enzyme E2 R1; E2 CDC34; UBC3; UBE2R1;
Gene ID : 997
mRNA Refseq : NM_004359
Protein Refseq : NP_004350
MIM : 116948
Uniprot ID : P49427
Chromosome Location : 19p13.3
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem;
Function : ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding;

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