Recombinant Human CDCA8, His-tagged

• Cat.No.: CDCA8-27492TH
• Product Overview: Recombinant fragment of Human Borealin/CDCA8 with a N terminal His tag; 283 amino acids, predicted molecular weight 31.6 kDa.

Specification

• Description: CDCA8 is a component of a chromosomal passenger complex required for stability of the bipolar mitotic spindle (Gassmann et al.
• Protein length: 262 amino acids
• Conjugation: HIS
• Molecular Weight: 31.600kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 50% Glycerol, 0.2M Sodium chloride, 20mM Tris HCl, 1mM EDTA, 1mM DTT, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMRKLA SFLKDFDREVEIRIKQIESDRQNLL KEVDNLYNIEILRLPKALREMNWLD YFALGGNKQALEEAATADLDITEIN KLTAEAIQTPLKSAKTRKVIQVDEM IVEEEEEEENERKNLQTARVKRCPP SKKRTQSIQGKGKGKRSSRANTVTP AVGRLEVSMVKPTPGLTPRFDSRVF KTPGLRTPAAGERIYNISGNGSPLA DSKEIFLTVPVGGGESLRLLASDLQ RHSIAQLDPEALGNIKKLSNRLAQI CSSIRTHK
• Sequence Similarities: Belongs to the borealin family.

Gene Information

• Gene Name: CDCA8 cell division cycle associated 8 [ Homo sapiens ]
• Official Symbol: CDCA8
• Synonyms: CDCA8; cell division cycle associated 8; borealin; BOR; DasraB; FLJ12042; MESRGP
• Gene ID: 55143
• mRNA Refseq: NM_018101
• Protein Refseq: NP_060571
• MIM: 609977
• Uniprot ID: Q53HL2
• Chromosome Location: 1p34.3
• Pathway: Aurora B signaling, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem
• Function: protein binding