Recombinant Human Twisted Gastrulation Homolog 1 (Drosophila)
Cat.No. : | TWSG1-1506H |
Product Overview : | Recombinant human TSG is a 199 amino acid protein containing the BMP/TGFβ binding portion of the full length TSG protein expressed inE. colicells. MW=22.2 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TWSG1-1506H |
Description : | Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex. |
Source : | E. coli. |
Quantity : | 50 μg. |
Purity : | Greater than 98% (determined by SDS-PAGE and HPLC analysis). |
Endotoxin Level : | < 0.1 ng per μg of rHu TSG (1EU/μg). |
Biological Activity : | Determined by its ability to neutralize BMP-6 induced alkaline phosphatase production by chondrogenic cells. The expected ED50 for this effect is < 2.0 μg/ml of TSG. |
Formulation : | Lyophilized from a sterile-filtered solution with no additives. |
Reconstitution : | Please Note: Always centrifuge product before opening vial. The lyophilized protein should be reconstituted with distilled, sterile water to a concentration of 0.1-1.0 mg/ml. For further dilution, carrier protein (0.1% BSA or HSA) should be added to avoid loss of bioactivity. |
Storage And Stability : | The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles. |
Gene Name : | TWSG1 twisted gastrulation homolog 1 (Drosophila) [ Homo sapiens ] |
Synonyms : | TWSG1; twisted gastrulation homolog 1 (Drosophila); TSG; Twisted gastrulation protein homolog 1; PSEC0250 |
Gene ID : | 57045 |
mRNA Refseq : | NM_020648 |
Protein Refseq : | NP_065699 |
UniProt ID : | Q9GZX9 |
Chromosome Location : | 18p11.3 |
MIM : | 605049 |
Function : | protein binding |
Products Types
◆ Recombinant Protein | ||
TWSG1-2972H | Recombinant Human TWSG1 Protein, His-tagged | +Inquiry |
TWSG1-355H | Recombinant Human TWSG1 Protein, His-tagged | +Inquiry |
Twsg1-9780M | Recombinant Mouse Twsg1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TWSG1-2975H | Recombinant Human TWSG1 Protein | +Inquiry |
TWSG1-162T | Active Recombinant Human TWSG1 Protein (211 aa), His-tagged | +Inquiry |
◆ Lysates | ||
TWSG1-1547MCL | Recombinant Mouse TWSG1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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