||Recombinant fragment, corresponding to amino acids 416-546 of Human CDT1 with N terminal His tag; Predicted MWt 16 kDa.
||The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.
||Lyophilised:Reconstitute with 92 μl aqua dest.
||Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
||Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequences of amino acids:
||KGVSQDLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLP ELARVLRSVFVSERKPALSMEVACARMVGSCCTIMSPG EMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAH ITARLAHQTRAEEGL
||Belongs to the Cdt1 family.