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Recombinant Human CETN1

Cat.No. : CETN1-27955TH
Product Overview : Recombinant fragment of Human Centrin 1 with N terminal proprietary tag, 36.63kDa.
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  • Gene Information
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Description : The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.
Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MASGFKKPSAASTGQKRKVAPKPEL TEDQKQEVREAFDLFDVDGSGTIDA KELKVAMRALGFEPRKEEMKKMISE VDREGTGKISFNDFLAVMTQKMSEK
Sequence Similarities : Belongs to the centrin family.Contains 4 EF-hand domains.
Gene Name : CETN1 centrin, EF-hand protein, 1 [ Homo sapiens ]
Official Symbol : CETN1
Synonyms : CETN1; centrin, EF-hand protein, 1; CETN; centrin-1; CEN1;
Gene ID : 1068
mRNA Refseq : NM_004066
Protein Refseq : NP_004057
MIM : 603187
Uniprot ID : Q12798
Chromosome Location : 18p11.32
Function : ATP binding; ATP-dependent helicase activity; G-protein beta/gamma-subunit complex binding; calcium ion binding; nucleic acid binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the current challenges in targeting CETN1 protein for clinical applications? 12/04/2021

One challenge is the need for a deeper understanding of the specific molecular mechanisms and pathways involving CETN1 in disease states.

Are there any known genetic variations or mutations in the CETN1 gene associated with clinical phenotypes? 05/15/2020

Certain genetic variations in the CETN1 gene have been linked to ciliopathies and developmental disorders, highlighting the clinical relevance of its genetic variations.

How does CETN1 protein contribute to cell cycle regulation? 03/01/2019

CETN1 is involved in centriole duplication and cell division processes, and its dysregulation can impact cell cycle control.

Are there any specific methods to measure CETN1 protein levels in patient samples? 03/31/2018

Various quantitative assays, such as enzyme-linked immunosorbent assay (ELISA) or mass spectrometry, can be used to measure CETN1 protein levels in clinical samples.

Are there any clinical trials investigating the role of CETN1 protein in cancer management? 03/19/2016

Currently, there are limited clinical trials specifically targeting CETN1 protein, but its role in cancer biology is being investigated in various studies.

Customer Reviews (3)

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Reviews
12/15/2019

    Their dedicated team of experts is prompt, knowledgeable, and readily available to tackle any hurdles or concerns I may encounter.

    10/10/2016

      By harnessing the power of the CETN1 protein, I can harness its outstanding quality and tap into its potential to obtain dependable and meaningful findings.

      06/02/2016

        Used in protein electron microscopy structure analysis.Great.

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