Recombinant Human CITED2, His-tagged CITED2-27073TH

Recombinant Human CITED2, His-tagged


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Recombinant Human CITED2, His-tagged

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Cat.No. : CITED2-27073TH
Product Overview : Recombinant fragment, corresponding to N terminal amino acids 1-160 of Human CITED2 with a His tag fused.
Description : The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of HIF1a to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Three transcript variants encoding the same protein have been found for this gene.
Conjugation : HIS
Source : E. coli
Form : Liquid
Storage buffer : Preservative: NoneConstituents: PBS
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the CITED family.
Gene Name : CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 [ Homo sapiens ]
Official Symbol : CITED2
Synonyms : CITED2; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; cbp/p300-interacting transactivator 2; MRG1;
Gene ID : 10370
mRNA Refseq : NM_001168388
Protein Refseq : NP_001161860
Uniprot ID : Q99967
Chromosome Location : 6q23.3
Pathway : HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem;
Function : LBD domain binding; chromatin binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity;

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