Recombinant Human CITED2, His-tagged

• Cat.No.: CITED2-27073TH
• Product Overview: Recombinant fragment, corresponding to N terminal amino acids 1-160 of Human CITED2 with a His tag fused.

Specification

• Description: The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of HIF1a to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Three transcript variants encoding the same protein have been found for this gene.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: PBS
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the CITED family.

Gene Information

• Gene Name: CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 [ Homo sapiens ]
• Official Symbol: CITED2
• Synonyms: CITED2; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; cbp/p300-interacting transactivator 2; MRG1
• Gene ID: 10370
• mRNA Refseq: NM_001168388
• Protein Refseq: NP_001161860
• Uniprot ID: Q99967
• Chromosome Location: 6q23.3
• Pathway: HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem
• Function: LBD domain binding; chromatin binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity