Recombinant Human COMMD1, His-tagged COMMD1-28013TH

Recombinant Human COMMD1, His-tagged

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Recombinant Human COMMD1, His-tagged

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Cat.No. : COMMD1-28013TH
Product Overview : Recombinant full length protein of Human COMMD1/MURR1 fused to 20 amino acid His-Tag at N-terminus, 23.3kDa.
Description : COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al.
Protein length : 190 amino acids
Conjugation : HIS
Molecular Weight : 23.300kDa inclusive of tags
Source : E. coli
Tissue specificity : Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.32% Tris HCl, 0.58% Sodium chloride, 20% Glycerol
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVPPEEFRP FLAKMRGILK SIASADMDFNQLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE SISTLISQPN
Sequence Similarities : Contains 1 COMM domain.
Gene Name : COMMD1 copper metabolism (Murr1) domain containing 1 [ Homo sapiens ]
Official Symbol : COMMD1
Synonyms : COMMD1; copper metabolism (Murr1) domain containing 1; C2orf5, chromosome 2 open reading frame 5 (MURR1); COMM domain-containing protein 1; copper metabolism gene MURR1; MGC27155; MURR1;
Gene ID : 150684
mRNA Refseq : NM_152516
Protein Refseq : NP_689729
MIM : 607238
Uniprot ID : Q8N668
Chromosome Location : 2p15
Pathway : TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function : copper ion binding; identical protein binding; metal ion binding; protein binding; protein homodimerization activity;

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