Recombinant Human COMMD7, His-tagged
Cat.No. : | COMMD7-27959TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 3-199 of Human COMMD7 with a N terminal His tag; 27kda. |
- Specification
- Gene Information
- Related Products
Description : | COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The prototype of this family, MURR1/COMMD1, suppresses NFkB by affecting the association of NF-kappaB with chromatin. COMMD7 (COMM domain-containing protein 7) interacts with COMMD1 via its COMM domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitution with 122 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | RLHCTEDPVPEAVGGDMQQLNQLGAQFSALTEVLFHFLTE PKEVERFLAQLSEFATTNQISLGSLRSIVKSLLLVPNG ALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPT LARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQ LKLVVKKGNQTENVYIELTLPQFYSFLHEMERVRTSME CFC |
Gene Name : | COMMD7 COMM domain containing 7 [ Homo sapiens ] |
Official Symbol : | COMMD7 |
Synonyms : | COMMD7; COMM domain containing 7; C20orf92, chromosome 20 open reading frame 92; COMM domain-containing protein 7; dJ1085F17.3; |
Gene ID : | 149951 |
mRNA Refseq : | NM_001099339 |
Protein Refseq : | NP_001092809 |
Uniprot ID : | Q86VX2 |
Chromosome Location : | 20q11 |
Function : | NF-kappaB binding; protein binding; |
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COMMD7-2574H | Recombinant Human COMMD7 protein, His-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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