"CYP1A2" Related Products


Recombinant Human CYP1A2

Cat.No.: CYP1A2-27559TH
Product Overview: Recombinant fragment of Human Cytochrome P450 1A2 with N terminal proprietary tag, 36.63kDa.
Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzymes endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3 untranslated region.
Protein length: 100 amino acids
Molecular Weight: 36.630kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Liver.
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the cytochrome P450 family.
Gene Name: CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 [ Homo sapiens ]
Official Symbol: CYP1A2
Synonyms: CYP1A2; cytochrome P450, family 1, subfamily A, polypeptide 2; cytochrome P450, subfamily I (aromatic compound inducible), polypeptide 2; cytochrome P450 1A2; CP12; P3 450;
Gene ID: 1544
mRNA Refseq: NM_000761
Protein Refseq: NP_000752
Uniprot ID: P05177
Chromosome Location: 15q24.1
Pathway: Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2, organism-specific biosystem; Biological oxidations, organism-specific biosystem; Caffeine metabolism, organism-specific biosystem; Caffeine metabolism, conserved biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem;
Function: aromatase activity; caffeine oxidase activity; demethylase activity; electron carrier activity; enzyme binding;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.