Recombinant Human DUSP19, His-tagged DUSP19-28073TH

Recombinant Human DUSP19, His-tagged

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Recombinant Human DUSP19, His-tagged

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Cat.No. : DUSP19-28073TH
Product Overview : DUSP19, 65-217aa, Human, His tag, E.coli
Description : Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al.
Conjugation : HIS
Tissue specificity : Expressed in the heart, lung, liver, and pancreas. The expression level in the pancreas is the highest.
Purity : >90% by SDS-PAGE
Sequence Similarities : Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.Contains 1 tyrosine-protein phosphatase domain.
Gene Name : DUSP19 dual specificity phosphatase 19 [ Homo sapiens ]
Official Symbol : DUSP19
Synonyms : DUSP19; dual specificity phosphatase 19; dual specificity protein phosphatase 19; DUSP17; SKRP1;
Gene ID : 142679
mRNA Refseq : NM_080876
Protein Refseq : NP_543152
MIM : 611437
Uniprot ID : Q8WTR2
Chromosome Location : 2q32.1
Function : JUN kinase phosphatase activity; MAP-kinase scaffold activity; hydrolase activity; mitogen-activated protein kinase kinase kinase binding; protein kinase activator activity;

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