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Recombinant Human DUSP19, His-tagged

Cat.No. : DUSP19-28073TH
Product Overview : DUSP19, 65-217aa, Human, His tag, E.coli
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  • Gene Information
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Description : Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al.
Conjugation : HIS
Tissue specificity : Expressed in the heart, lung, liver, and pancreas. The expression level in the pancreas is the highest.
Purity : >90% by SDS-PAGE
Sequence Similarities : Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.Contains 1 tyrosine-protein phosphatase domain.
Gene Name : DUSP19 dual specificity phosphatase 19 [ Homo sapiens ]
Official Symbol : DUSP19
Synonyms : DUSP19; dual specificity phosphatase 19; dual specificity protein phosphatase 19; DUSP17; SKRP1;
Gene ID : 142679
mRNA Refseq : NM_080876
Protein Refseq : NP_543152
MIM : 611437
Uniprot ID : Q8WTR2
Chromosome Location : 2q32.1
Function : JUN kinase phosphatase activity; MAP-kinase scaffold activity; hydrolase activity; mitogen-activated protein kinase kinase kinase binding; protein kinase activator activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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