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Recombinant Human FCER2, GST-tagged

Cat.No.: FCER2-27296TH
Product Overview: Recombinant GST tagged fragment, corresponding to amino acids 48-248 of Human CD23; 201 amino acids, 48kDa.
Description: The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Conjugation: GST
Source: E. coli
Form: Liquid
Purity: Purified via GST Tag
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5BSA and Azide free
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Contains 1 C-type lectin domain.
Gene Name: FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) [ Homo sapiens ]
Official Symbol: FCER2
Synonyms: FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J;
Gene ID: 2208
mRNA Refseq: NM_001207019
Protein Refseq: NP_001193948
MIM: 151445
Uniprot ID: P06734
Chromosome Location: 19p13.3
Pathway: Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-3 Signaling Pathway, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem;
Function: IgE binding; binding; integrin binding; metal ion binding; receptor activity;

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