Recombinant Human GK

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Recombinant Human GK

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Cat.No. : GK-29028TH
Product Overview : Recombinant fragment of Human Glycerol kinase (aa 2-94) with a N terminal proprietary tag: predicted molecular weight 35.86 kDa.
Description : The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein length : 93 amino acids
Molecular Weight : 35.860kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : AASKKAVLGP LVGAVDQGTS STRFLVFNSK TAELLSHHQV EIKQEFPREG WVEQDPKEIL HSVYECIEKT CEKLGQLNID ISNIKAIGVS NQR
Sequence Similarities : Belongs to the FGGY kinase family.
Gene Name : GK glycerol kinase [ Homo sapiens ]
Official Symbol : GK
Synonyms : GK; glycerol kinase; GK1; GKD;
Gene ID : 2710
mRNA Refseq : NM_000167
Protein Refseq : NP_000158
MIM : 300474
Uniprot ID : P32189
Chromosome Location : Xp21.3
Pathway : Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem; Glycerolipid metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem;
Function : ATP binding; glycerol kinase activity; glycerol kinase activity; nucleotide binding; transferase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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