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Recombinant Human ICK

Cat.No.: ICK-28676TH
Product Overview: Recombinant full length Human ICK with an N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; MWt 98kDa.
Description: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
Protein length: 632 amino acids
Molecular Weight: 98.000kDa inclusive of tags
Source: Baculovirus
Biological activity: The Specific activity of ICK-28676TH was determined to be 4.8 nmol/min/mg.
Form: Liquid
Purity: by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name: ICK intestinal cell (MAK-like) kinase [ Homo sapiens ]
Official Symbol: ICK
Synonyms: ICK; intestinal cell (MAK-like) kinase; serine/threonine-protein kinase ICK; KIAA0936; LCK2; MGC46090; MRK;
Gene ID: 22858
mRNA Refseq: NM_016513
Protein Refseq: NP_057597
MIM: 612325
Uniprot ID: Q9UPZ9
Chromosome Location: 6p12.3-p11.2
Function: ATP binding; cyclin-dependent protein kinase activity; magnesium ion binding; nucleotide binding; protein serine/threonine kinase activity;

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