Recombinant Human ILF2, His-tagged
Cat.No. : | ILF2-29033TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 25-390 of Human ILF2 with an N terminal His tag; Predicted MWt 41kDa. |
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Description : | Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitute with 108 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | PFVPHIPFDFYLCEMAFPRVKPAPD ETSFSEALLKRNQDL APNSAEQASILSLVTKINNVIDNLI VAPGTFEVQIEEV RQVGSYKKGTMTTGHNVADLVVILK ILPTLEAVAALGN KVVESLRAQDPSEVLTMLTNETGFE ISSSDATVKILIT TVPPNLRKLDPELHLDIKVLQSALA AIRHARWFEENASQSTVKVLIRLLK DLRIRFPGFEPLTPWILDLLGHYAV MNN PTRQPLALNVAYRRCLQILAAGLFL PGSVGITDPCESG NFRVHTVMTLEQQDMVCYTAQTLVR ILSHGGFRKILGQ EGDASYLASEISTWDGVIVTPSEKA YEKPPEKKEGEEE EENTEEPPQGEEEESMETQE |
Sequence Similarities : | Contains 1 DZF domain. |
Gene Name : | ILF2 interleukin enhancer binding factor 2, 45kDa [ Homo sapiens ] |
Official Symbol : | ILF2 |
Synonyms : | ILF2; interleukin enhancer binding factor 2, 45kDa; interleukin enhancer binding factor 2, 45kD; interleukin enhancer-binding factor 2; NF45; |
Gene ID : | 3608 |
mRNA Refseq : | NM_004515 |
Protein Refseq : | NP_004506 |
MIM : | 603181 |
Uniprot ID : | Q12905 |
Chromosome Location : | 1q21.3 |
Function : | ATP binding; DNA binding; double-stranded RNA binding; protein binding; transferase activity; |
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ILF2-4523M | Recombinant Mouse ILF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ILF2-5222HCL | Recombinant Human ILF2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionAs an immunomodulatory factor, ILF2 has a potential application prospect in tumor immunotherapy, but its specific role and application value still need to be further studied and clinical trials.
The regulation of ILF2 signaling pathway may involve other transcription factors, cytokines, protein kinases and other factors, including IRF4, STAT1, NF-κB and so on.
ILF2 the relationship between structure and function has not been fully elucidated, by studying aspects such as its domain structure, protein interactions can be insight into its function mechanism.
ILF2 is involved in cell proliferation, apoptosis, inflammatory response, antiviral immunity and other biological processes, but its specific function and mechanism still need to be further studied.
This protein is related to some inflammatory diseases, tumors and immune regulation, such as liver cancer, breast cancer, rheumatoid arthritis and so on.
Customer Reviews (3)
Write a reviewNo adverse reactions, small side effects.
The safety is very high, and no side effects are found after long-term use.
Easy to operate, easy to use, will recommend to others.
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