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Recombinant Human ILF2, His-tagged

Cat.No. : ILF2-29033TH
Product Overview : Recombinant fragment, corresponding to amino acids 25-390 of Human ILF2 with an N terminal His tag; Predicted MWt 41kDa.
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Description : Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 108 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : PFVPHIPFDFYLCEMAFPRVKPAPD ETSFSEALLKRNQDL APNSAEQASILSLVTKINNVIDNLI VAPGTFEVQIEEV RQVGSYKKGTMTTGHNVADLVVILK ILPTLEAVAALGN KVVESLRAQDPSEVLTMLTNETGFE ISSSDATVKILIT TVPPNLRKLDPELHLDIKVLQSALA AIRHARWFEENASQSTVKVLIRLLK DLRIRFPGFEPLTPWILDLLGHYAV MNN PTRQPLALNVAYRRCLQILAAGLFL PGSVGITDPCESG NFRVHTVMTLEQQDMVCYTAQTLVR ILSHGGFRKILGQ EGDASYLASEISTWDGVIVTPSEKA YEKPPEKKEGEEE EENTEEPPQGEEEESMETQE
Sequence Similarities : Contains 1 DZF domain.
Gene Name : ILF2 interleukin enhancer binding factor 2, 45kDa [ Homo sapiens ]
Official Symbol : ILF2
Synonyms : ILF2; interleukin enhancer binding factor 2, 45kDa; interleukin enhancer binding factor 2, 45kD; interleukin enhancer-binding factor 2; NF45;
Gene ID : 3608
mRNA Refseq : NM_004515
Protein Refseq : NP_004506
MIM : 603181
Uniprot ID : Q12905
Chromosome Location : 1q21.3
Function : ATP binding; DNA binding; double-stranded RNA binding; protein binding; transferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the potential applications of ILF2 in tumor immunotherapy? 09/19/2019

As an immunomodulatory factor, ILF2 has a potential application prospect in tumor immunotherapy, but its specific role and application value still need to be further studied and clinical trials.

Do the regulators of the ILF2 signaling pathway interact with other protein mushrooms? 08/16/2019

The regulation of ILF2 signaling pathway may involve other transcription factors, cytokines, protein kinases and other factors, including IRF4, STAT1, NF-κB and so on.

Does the structure-function relationship of ILF2 have to do with it? 06/18/2019

ILF2 the relationship between structure and function has not been fully elucidated, by studying aspects such as its domain structure, protein interactions can be insight into its function mechanism.

In the existing studies, what are the main biological functions of ILF2? 04/30/2019

ILF2 is involved in cell proliferation, apoptosis, inflammatory response, antiviral immunity and other biological processes, but its specific function and mechanism still need to be further studied.

What diseases or pathological processes are ILF2 associated with? 03/23/2019

This protein is related to some inflammatory diseases, tumors and immune regulation, such as liver cancer, breast cancer, rheumatoid arthritis and so on.

Customer Reviews (3)

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Reviews
11/12/2021

    No adverse reactions, small side effects.

    01/19/2021

      The safety is very high, and no side effects are found after long-term use.

      12/02/2020

        Easy to operate, easy to use, will recommend to others.

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