| Description : |
Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE) rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid associated lung collectin that mediates innate and adaptive immune responses in the lungs. |
| Conjugation : |
HIS |
| Source : |
E. coli |
| Form : |
Lyophilised:Reconstitute with 140 μl aqua dest. |
| Storage buffer : |
Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
| Storage : |
Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
EKRELEGKLATLSDQVNRRDFESEK RLRKDLKRTKALLAD AQLMLDHLKNSAPSKREIAQLKNQL EESEFTCAAAVKA RKAMEVEIEDLHLQIDDIAKAKTAL EEQLSRLQREKNEIQNRLEEDQEDM NELMKKHKAAVAQASRDLAQINDLQ AQL EEANKEKQELQEKLQALQSQVEFLE QSMVDKSLVSRQE AKIRELETRLEFERTQVKRLESLAS RLKENMEKLTEERDQ RIAAENREKEQNKRLQRQLRDTKEE MGELARKEAEASR KKHELEMDLESLEAANQSLQADLKL AFKRIGDLQAAIE DEMESDENEDLINSEGDSDVDSELE DRVDGVKSWLSKNKG PSKAASDDGSLKSSSPTSYWKSLAP DRSDDEHDPLDNT SRPRYSHSYLSDSDTEAKLTETNA |
