Recombinant Human SEPT1, HIS-tagged

• Cat.No.: SEPT1-30600TH
• Product Overview: Recombinant fragment, corresponding to amino acids 1-174 of Human SEPT1 with N terminal His tag. MWt ~20kDa

Specification

• Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimers disease.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitution with 119 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: (Amino acid sequence (Sequence determined by 5 Sequencing))MDKEYVGFAALPNQLHRKSVKKGFDF TLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWL PVVKFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFIS PFGRGLRPLDVAFLRAVHEKVNIIPVIGKADA

Gene Information

• Gene Name: SEPT1 septin 1 [ Homo sapiens ]
• Official Symbol: SEPT1
• Synonyms: SEPT1; septin 1; DIFF6; septin-1; PNUTL3
• Gene ID: 1731
• mRNA Refseq: NM_052838
• Protein Refseq: NP_443070
• MIM: 612897
• Uniprot ID: Q8WYJ6
• Chromosome Location: 16p11.1
• Pathway: Aurora B signaling, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem
• Function: GTP binding; nucleotide binding; protein binding