Recombinant Human SIK2

• Cat.No.: SIK2-30089TH
• Product Overview: Recombinant full length Human Snf1lk2 with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 insect cell expression system; MWt 150kDa.

Specification

• Description: Serine/threonine-protein kinase SIK2 is an enzyme that in humans is encoded by the SIK2 gene. SNF1LK2 has been shown to interact with CRTC2.
• Biological activity: The specific activity of SIK2-30089TH was determined to be 112 nmol/min/mg.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.Contains 1 protein kinase domain.Contains 1 UBA domain.

Gene Information

• Gene Name: SIK2 salt-inducible kinase 2 [ Homo sapiens ]
• Official Symbol: SIK2
• Synonyms: SIK2; salt-inducible kinase 2; SNF1 like kinase 2 , SNF1LK2; serine/threonine-protein kinase SIK2; DKFZp434K1115; KIAA0781; LOH11CR1I; QIK
• Gene ID: 23235
• mRNA Refseq: NM_015191
• Protein Refseq: NP_056006
• MIM: 608973
• Uniprot ID: Q9H0K1
• Chromosome Location: 11q23.1
• Pathway: LKB1 signaling events, organism-specific biosystem
• Function: ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity