Recombinant Human SUV420H1

• Cat.No.: SUV420H1-31486TH
• Product Overview: Recombinant fragment, corresponding to amino acids 2-387 of Human SUV420h1 with N-terminal proprietary tag, 70 kDa.

Specification

• Description: This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Two alternatively spliced transcript variants have been found for this gene.
• Source: E. coli
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 30% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the histone-lysine methyltransferase family. Suvar4-20 subfamily.Contains 1 SET domain.

Gene Information

• Gene Name: SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: SUV420H1
• Synonyms: SUV420H1; suppressor of variegation 4-20 homolog 1 (Drosophila); histone-lysine N-methyltransferase SUV420H1; CGI 85; KMT5B
• Gene ID: 51111
• mRNA Refseq: NM_017635
• Protein Refseq: NP_060105
• MIM: 610881
• Uniprot ID: Q4FZB7
• Chromosome Location: 11q13.2
• Pathway: Glucocorticoid receptor regulatory network, organism-specific biosystem; Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem
• Function: histone methyltransferase activity (H4-K20 specific); histone-lysine N-methyltransferase activity; methyltransferase activity; transferase activity