Recombinant Human C-terminal Binding Protein 1
Cat.No. : | CTBP1-2027H |
Product Overview : | Recombinant human CtBP1 was expressed inE.coliand purified by using conventional chromatography techniques. MW = 47.5 kDa (440aa). |
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- Gene Information
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Cat. No. : | CTBP1-2027H |
Description : | C-terminal-binding protein 1 isoform 1, also known as CtBP1, is expressed from embryo to adult. This protein binds to the C-terminus of adenovirus E1A. It is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. Also, CtBP1 associates in complexes with histone deacetylases (HDAC), the G9a histone methyltransferase, and LSD1 histone demethylase illustrating its role in transcriptional repression. |
Source : | E. coli. |
Sequences Of Amino Acids : | MGSSHLLNKG LPLGVRPPIM NGPLHPRPLV ALLDGRDCTV EMPILKDVAT VAFCDAQSTQ EIHEKVLNEA VGALMYHTIT LTREDLEKFK ALRIIVRIGS GFDNIDIKSA GDLGIAVCNV PAASVEETAD STLCHILNLY RRATWLHQAL REGTRVQSVE QIREVASGAA RIRGETLGII GLGRVGQAVA LRAKAFGFNV LFYDPYLSDG VERALGLQRV STLQDLLFHS DCVTLHCGLN EHNHHLINDF TVKQMRQGAF LVNTARGGLV DEKALAQALK EGRIRGAALD VHESEPFSFS QGPLKDAPNL ICTPHAAWYS EQASIEMREE AAREIRRAIT GRIPDSLKNC VNKDHLTAAT HWASMDPAVV HPELNGAAYR YPPGVVGVAP TGIPAAVEGI VPSAMSLSHG LPPVAHPPHA PSPGQTVKPE ADRDHASDQL. |
Purity : | > 90% by SDS – PAGE. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 100mM NaCl, 10% glycerol. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles. |
Gene Name : | CTBP1 C-terminal binding protein 1 [ Homo sapiens ] |
Synonyms : | CTBP1; C-terminal binding protein 1; BARS; MGC104684; brefeldin A-ribosylated substrate; C-terminal-binding protein 1; CtBP1; EC 1.1.1.-; CTBP |
Gene ID : | 1487 |
mRNA Refseq : | NM_001012614 |
Protein Refseq : | NP_001012632 |
MIM : | 602618 |
UniProt ID : | Q13363 |
Chromosome Location : | 4p16 |
Pathway : | Chronic myeloid leukemia; Notch signaling pathway; Pathways in cancer; Wnt signaling pathway |
Function : | NAD or NADH binding; cofactor binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; protein C-terminus binding; protein binding; protein domain specific binding; transcription factor activity; transcription factor binding; transcription repressor activity |
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CTBP1-2053H | Recombinant Human CTBP1 Protein, GST-tagged | +Inquiry |
CTBP1-1307R | Recombinant Rat CTBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CTBP1-640H | Recombinant Human CTBP1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CTBP1-7216HCL | Recombinant Human CTBP1 293 Cell Lysate | +Inquiry |
CTBP1-7215HCL | Recombinant Human CTBP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCTBP1 is a transcriptional co-repressor, regulating gene expression.
Genetic changes in CTBP1 affect cell development and differentiation.
CTBP1 collaborates with transcription factors, influencing gene regulation.
CTBP1 is involved in developmental processes and cell differentiation.
Targeting CTBP1 could treat diseases with abnormal gene expression, including cancer.
It plays a key role in transcriptional repression, impacting gene activity.
Altered CTBP1 activity is associated with cancer progression.
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