||Recombinant Human adenosylmethionine decarboxylase 1 is expressed inE. coli.The molecular weight of the recombinant Human AMD1 is 38.3 kDaand contains 334 amino acids. AMD1 contains T7 tag at N-terminus.
||AMD1 catalyzes the removal of the carboxylate group of S-adenosylmethionine in the polyamine biosynthesis pathway. Adenosylmethionine decarboxylase is an enzyme which catalyzes the conversion of S-Adenosyl methionineto S-adenosyl-5"-3-methylpropylamine. This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified.
||Greater than 95.0% as determined by SDS-PAGE.
||Sterile Filtered clear solution.
||AdoMetDC at 0.1mg/ml, 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
||S-Adenosylmethionine Decarboxylase although stable at 14℃ for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).