Recombinant Human Adenosylmethionine Decarboxylase 1, T7-tagged AMD1-577H

Recombinant Human Adenosylmethionine Decarboxylase 1, T7-tagged


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Recombinant Human Adenosylmethionine Decarboxylase 1, T7-tagged

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Cat. No. : AMD1-577H.
Product Overview : Recombinant Human adenosylmethionine decarboxylase 1 is expressed inE. coli.The molecular weight of the recombinant Human AMD1 is 38.3 kDaand contains 334 amino acids. AMD1 contains T7 tag at N-terminus.
Description : AMD1 catalyzes the removal of the carboxylate group of S-adenosylmethionine in the polyamine biosynthesis pathway. Adenosylmethionine decarboxylase is an enzyme which catalyzes the conversion of S-Adenosyl methionineto S-adenosyl-5"-3-methylpropylamine. This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified.
Source : E. coli.
Purity : Greater than 95.0% as determined by SDS-PAGE.
Physical Appearance : Sterile Filtered clear solution.
Formulation : AdoMetDC at 0.1mg/ml, 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
Storage : S-Adenosylmethionine Decarboxylase although stable at 14℃ for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Gene Name : AMD1 adenosylmethionine decarboxylase 1 [ Homo sapiens ]
Synonyms : adenosylmethionine decarboxylase 1; AMD1; AMD; SAMDC; ADOMETDC; FLJ26964; DKFZp313L1234; S-adenosylmethionine decarboxylase 1; S-adenosylmethionine decarboxylase 1
Gene ID : 262
mRNA Refseq : NM_001033059
Protein Refseq : NP_001028231
MIM : 180980
UniProt ID : Q5VXN4
Chromosome Location : 6q21-q22
Pathway : Arginine and proline metabolism; Cysteine and methionine metabolism; Metabolic pathways; Metabolism of amino acids and derivatives; Metabolism of polyamines
Function : lyase activity; Adenosylmethionine decarboxylase activity; adenosylmethionine decarboxylase activity

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