Recombinant Human PLA2G7, His-tagged
Cat.No. : | PLA2G7-581H |
Product Overview : | Recombinant Human phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) is expressed inE. coliwith N-terminal His-tagged. The molecular weight of the recombinant human PLA2G7 is 46.4 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PLA2G7-581H. |
Description : | Platelet-activating factor acetylhydrolase (PAF-AH) is an extracellular phospholipase A2 which hydrolyzes the acetyl group at the sn-2 position of phospholipids. Two main types of PAF-AH have been characterized, namely the secreted (i.e. plasma) and intracellular enzymes, which are encoded on individual genes and share only 41% homology at the amino acid level. PAF deacetylation by PAF-AH causes loss of biological activity, making PAF-AH potential useful as an anti-inflammation therapy. Human recombinant PAF-AH was characterized using 2-Thio PAF as a substrate, which upon hydrolysis by PAF-AH releases a free thiol that reacts with 5,5-dithio-bis(2-dinitrobenzoic acid) (DTNB) to produce 5-thio-2-nitrobenzoic acid (TNB) with an absorbance maximum at 412 nm. |
Source : | E. coli. |
Purity : | Greater than 95% as determined by SDS-PAGE. |
Formulation : | 100 mM Sodium phosphate, pH 7.2, containing 100 mM sodium chloride and 20% glycerol. |
Storage : | -80℃. 1 year. |
Gene Name : | PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [ Homo sapiens ] |
Synonyms : | PLA2G7; phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma); LP-PLA2; Platelet-Activating Factor Acetylhydrolase; PAF-AH;Lipoprotein PLA2; LDL-PLA(2); gVIIA-PLA2; PAF 2-acylhydrolase; PAF acetylhydrolase; group-VIIA phospholipase A2; LDL-associated phospholipase A2; PAFAH; lipoprotein-associated phospholipase A2; LDL-PLA2; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase |
Gene ID : | 7941 |
mRNA Refseq : | NM_001168357 |
Protein Refseq : | NP_001161829 |
MIM : | 601690 |
UniProt ID : | Q13093 |
Chromosome Location : | 6p21.2-p12 |
Pathway : | Ether lipid metabolism; Metabolic pathways; Diabetes pathways |
Function : | 1-alkyl-2-acetylglycerophosphocholine esterase activity; hydrolase activity; phospholipid binding |
Products Types
◆ Recombinant Protein | ||
PLA2G7-2593H | Recombinant Human PLA2G7 Protein, His-tagged | +Inquiry |
PLA2G7-1145H | Active Recombinant Human PLA2G7 protein(Met1-Asn441), His-tagged | +Inquiry |
Pla2g7-1184R | Recombinant Rat Pla2g7 Protein, His-tagged | +Inquiry |
PLA2G7-37H | Recombinant Human PLA2G7 Protein, His-tagged | +Inquiry |
PLA2G7-866M | Recombinant Mouse PLA2G7 Protein (Met1-Asn440), His-tagged | +Inquiry |
◆ Lysates | ||
PLA2G7-2057HCL | Recombinant Human PLA2G7 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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