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Recombinant Mouse Telomerase Reverse Transcriptase

Cat. No.: Tert-574M.
Product Overview: Recombinant Mouse telomerase reverse transcriptase is expressed inE. coli. TERT encoding 174-341 amino acids. The molecular weight of the recombinant Tert is 46 kDa.
Description: Telomeres are specialized structures at the ends of eukaryotic chromosomes which appear to function in chromosome stabilization, positioning and replication. At each cell division, the length of telomeric TTAGGG DNA repeats is shortened and cells ultimately stop dividing. Telomerase is a reverse transcriptase that synthesizes telomere DNA thereby compensating for telomere loss. Telomerease is expressed mainly in the nucleus of proliferating cells and lymphocytes.
Source: E. coli.
Purity: >90%.
Physical Appearance: Sterile filtered liquid.
Formulation: Telomerase protein at 100μg/ml in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
Storage: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.
Gene Name: Tert telomerase reverse transcriptase [ Mus musculus ]
Synonyms: telomerase reverse transcriptase; Tert; TR; TP2; TRT; EST2; TCS1; hEST2; MGC150124; telomerase catalytic subunit; telomerase-associated protein 2
Gene ID: 21752
mRNA Refseq: NM_009354
Protein Refseq: NP_033380
UniProt ID: O14746
Chromosome Location: 13 C1
Function: nucleotidyltransferase activity; DNA binding; RNA binding;protein binding; RNA-directed DNA polymerase activity; telomerase activity; telomeric template RNA reverse transcriptase activity; transferase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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