"ASPH" Related Products

Expand

Recombinant Human Aspartate beta-hydroxylase, His-tagged

Cat. No.: ASPH-1940H
Product Overview: Recombinant human ASPH protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 24.5 kDa (217aa).
Description: ASPH (Aspartate beta-hydroxylase) is a widely-expressed type II membrane protein involved in calcium homeostasis. Located in the endoplasmic reticulum, ASPH specifically hydroxylates an Asp or Asn residue in the epidermal growth factor-like (EGF) domains of several proteins, using iron as a cofactor. While all ASPH variants are expressed in skeletal muscle, only some are detected in heart, brain, pancreas, placenta, lung, liver, and kidney tissues.
Source: E.coli.
Purity: > 90% by SDS – PAGE.
Physical Appearance: Liquid.
Formulation: In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol.
Concentration: 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MFDLVDYEEV LGKLGIYDAD GDGDFDVDDA KVLL GLKERS TSEPAV PPEE AEPHTEPEEQ VPVEAEPQNI EDEAKEQIQS LLHEMVHAEH ETEHSYHVEE TVSQDCNQDM EEMMSEQENP DSSEPVVEDE RLHHDTDDVT YQVYEEQAVY EPLENEGIEI TEVTAPPEDN PVEDSQVIVE EVSIFPVEEQ QEVPPDT.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: ASPH aspartate beta-hydroxylase [ Homo sapiens ]
Synonyms: ASPH; aspartate beta-hydroxylase; AAH; BAH; HAAH; JCTN; junctin; CASQ2BP1; aspartyl/asparaginyl beta-hydroxylase; aspartyl/asparaginyl beta-hydroxylase; humbug; junctate; A beta H-J-J; cardiac junctin; ASP beta-hydroxylase; peptide-aspartate beta-dioxygenase; aspartyl/asparaginyl-beta-hydroxylase; EC 1.14.11.1
Gene ID: 444
mRNA Refseq: NM_001164750
Protein Refseq: NP_001158222
MIM: 600582
UniProt ID: Q12797
Chromosome Location: 8q12
Function: Binding;calcium ion binding;electron carrier activity;oxidoreductase activity;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;peptide-aspartate beta-dioxygenase activity;structural constituent of muscle;structural molecule activity.

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.