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Recombinant Human Aspartate beta-hydroxylase, His-tagged

Cat.No. : ASPH-1940H
Product Overview : Recombinant human ASPH protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 24.5 kDa (217aa).
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Cat. No. : ASPH-1940H
Description : ASPH (Aspartate beta-hydroxylase) is a widely-expressed type II membrane protein involved in calcium homeostasis. Located in the endoplasmic reticulum, ASPH specifically hydroxylates an Asp or Asn residue in the epidermal growth factor-like (EGF) domains of several proteins, using iron as a cofactor. While all ASPH variants are expressed in skeletal muscle, only some are detected in heart, brain, pancreas, placenta, lung, liver, and kidney tissues.
Source : E.coli.
Purity : > 90% by SDS – PAGE.
Physical Appearance : Liquid.
Formulation : In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MFDLVDYEEV LGKLGIYDAD GDGDFDVDDA KVLL GLKERS TSEPAV PPEE AEPHTEPEEQ VPVEAEPQNI EDEAKEQIQS LLHEMVHAEH ETEHSYHVEE TVSQDCNQDM EEMMSEQENP DSSEPVVEDE RLHHDTDDVT YQVYEEQAVY EPLENEGIEI TEVTAPPEDN PVEDSQVIVE EVSIFPVEEQ QEVPPDT.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : ASPH aspartate beta-hydroxylase [ Homo sapiens ]
Synonyms : ASPH; aspartate beta-hydroxylase; AAH; BAH; HAAH; JCTN; junctin; CASQ2BP1; aspartyl/asparaginyl beta-hydroxylase; aspartyl/asparaginyl beta-hydroxylase; humbug; junctate; A beta H-J-J; cardiac junctin; ASP beta-hydroxylase; peptide-aspartate beta-dioxygenase; aspartyl/asparaginyl-beta-hydroxylase; EC 1.14.11.1
Gene ID : 444
mRNA Refseq : NM_001164750
Protein Refseq : NP_001158222
MIM : 600582
UniProt ID : Q12797
Chromosome Location : 8q12
Function : Binding;calcium ion binding;electron carrier activity;oxidoreductase activity;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;peptide-aspartate beta-dioxygenase activity;structural constituent of muscle;structural molecule activity.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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