Recombinant Human CRYZL1, His-tagged

• Cat.No.: CRYZL1-2404H
• Product Overview: Recombinant human CRYZL1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques, 40.8 kDa (369aa).

Specification

• Cat. No.: CRYZL1-2404H
• Description: CRYZL1, also known as quinone oxidoreductase, is a protein that has sequence similarity to zeta crystalline. This Protein is present at low levels in human lens tissue. It has NADPH-dependent quinone reductase activity distinct from other known quinone reductases, and may play a role as a pH response element-binding protein. CRYZL1 is expressed at various levels in heart, brain, skeletal muscle, kidney, pancreas, liver and lung.
• Source: E.coli.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 2mM DTT, 0.1M NaCl, 20% glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MKGLYFQQSS TDEEITFVFQ EKEDLPVTED NFVKLQVKAC ALSQINTKLL AEMKMKKDLF PVGREIAGIV LDVGSKVSFF QPDDEVVGIL PLDSEDPGLC EVVRVHEHYL VHKPEKVTWT EAAGSIRDGV RAYTALHYLS HLSPGKSVLI MDGASAFGTI AIQLAHHRGA KVISTACSLE DKQCLERFRP PIARVIDVSN GKVHVAESCL EETGGLGVDI VLDAGVRLYS KDDEPAVKLQ LLPHKHDIIT LLGVGGHWVT TEENLQLDPP DSHCLFLKGA TLAFLNDEVW NLSNVQQGKY LCILKDVMEK LSTGVFRPQL DEPIPLYEAK VSMEAVQKNQ GRKKQVVQF.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CRYZL1 crystallin, zeta (quinone reductase)-like 1 [ Homo sapiens ]
• Synonyms: crystallin, zeta (quinone reductase)-like 1; 4P11; QOH-1; CRYZL1; quinone oxidoreductase-like protein 1; protein 4P11; zeta-crystallin homolog; quinone reductase-like 1;quinone oxidoreductase homolog 1 ; crystallin, zeta-like 1; Zeta-crystallin homolog; EC 1.-.-.-; human quinone oxidoreductase homolog-19
• Gene ID: 9946
• mRNA Refseq: NM_145858
• Protein Refseq: NP_665857
• MIM: 603920
• UniProt ID: O95825
• Chromosome Location: 21q21.3
• Function: NADP or NADPH binding; NADPH:quinone reductase activity; binding; oxidoreductase activity; zinc ion binding