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Recombinant Human TAF1A

Cat. No.: TAF1A-2448H
Product Overview: Recombinant Human TAF1A was produced inE. coli.
Description: I2PP2A(β), also termed TAF-1, inhibits protein phosphatase 2A (PP2A) potently with ki ~ 0.1 - 0.5 nm with myelin basic protein, histone H1 and other substrates but not with casein. It stimulates PP1 and regulates histone binding to DNA, transcriptional activity and chromatin condensation.
Source: E. coli.
Purity: > 90% by SDS-PAGE, apparent Mr ~ 41-kDa.
Supplied: 250 ng in 50 l 50 mM Tris-HCl pH 7.0 buffer containing 14 mM -mercaptoethanol, 1 mM benzamidine, 0.1 mM phenylmethanesulfonyl fluoride, 1 mM EDTA and 0.1% Brij-35 and 10% glycerol.
Storage: Maintain preparations in aliquots at -70 °C. Avoid repeated thawing.
Gene Name: TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa [ Homo sapiens ]
Synonyms: TAF1A; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa; SL1; RAFI48; TAFI48; MGC:17061; TATA box-binding protein-associated factor RNA polymerase I subunit A; SL1, 48kD subunit; TBP-associated factor 1A; transcription factor SL1; TATA box-binding protein-associated factor 1A; transcription initiation factor SL1/TIF-IB subunit A; RNA polymerase I-specific TBP-associated factor 48 kDa; MGC:17061; OTTHUMP00000035654
Gene ID: 9015
mRNA Refseq: NM_005681
Protein Refseq: NP_005672
MIM: 604903
UniProt ID: Q15573
Chromosome Location: 1q42
Pathway: Transcription
Function: DNA binding; RNA polymerase I transcription factor activity; general RNA polymerase II transcription factor activity; protein binding

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