I2PP2A(β), also termed TAF-1, inhibits protein phosphatase 2A (PP2A) potently with ki ~ 0.1 - 0.5 nm with myelin basic protein, histone H1 and other substrates but not with casein. It stimulates PP1 and regulates histone binding to DNA, transcriptional activity and chromatin condensation.
Source :
E. coli.
Purity :
> 90% by SDS-PAGE, apparent Mr ~ 41-kDa.
Supplied :
250 ng in 50 l 50 mM Tris-HCl pH 7.0 buffer containing 14 mM -mercaptoethanol, 1 mM benzamidine, 0.1 mM phenylmethanesulfonyl fluoride, 1 mM EDTA and 0.1% Brij-35 and 10% glycerol.
Storage :
Maintain preparations in aliquots at -70 °C. Avoid repeated thawing.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.