Active Recombinant Human ABL1 protein, GST-tagged

• Cat.No.: ABL1-783H
• Product Overview: Active Recombinant Human ABL1 protein(Pro 137-Ser 554)(NP_009297.2) was expressed in Insect Cells, fused with the GST tag at the N-terminus.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Protein Length: 137-554 aa
• Form: Supplied as sterile 50mM Tris, 100mM NaCl, 0.5mM PMSF, 0.5mM EDTA, 0.5mM Reduced Glutathione, pH 8.0.
• Bio-activity: The specific activity was determined to be 240 nmol/min/mg using synthetic Abl peptide (EAIYAAPFAKKK) as substrate.
• Molecular Mass: The recombinant human ABL1/GST chimera consists of 645 amino acids and predicts a molecular mass of 74 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 92 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.2 ug/ul
• protein Refseq-Weblink: http://www.ncbi.nlm.nih.gov/protein/NP_005148.2
• Unit ID: P00519
• Unit ID-Weblink: https://www.uniprot.org/uniprotkb/P00519

Gene Information

• Gene Name: ABL1 c-abl oncogene 1, non-receptor tyrosine kinase [ Homo sapiens ]
• Official Symbol: ABL1
• Synonyms: ABL1; c-abl oncogene 1, non-receptor tyrosine kinase; ABL, c abl oncogene 1, receptor tyrosine kinase, v abl Abelson murine leukemia viral oncogene homolog 1; tyrosine-protein kinase ABL1; c ABL; JTK7; p150; proto-oncogene c-Abl; bcr/c-abl oncogene protein; Abelson tyrosine-protein kinase 1; c-abl oncogene 1, receptor tyrosine kinase; proto-oncogene tyrosine-protein kinase ABL1; v-abl Abelson murine leukemia viral oncogene homolog 1; ABL; c-ABL; v-abl; bcr/abl
• Gene ID: 25
• mRNA Refseq: NM_005157
• protein Refseq: NP_005148
• MIM: 189980