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Recombinant Mouse CD27 Antigen, Fc Chimera

Cat.No. : Cd27-3258M
Product Overview : Recombinant mouse Cd27 protein (Met 1-Ile 189), fused with the Fc region of human IgG1 at the C-terminus, was expressed inHuman Cells.
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  • Gene Information
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Cat. No. : Cd27-3258M
Description : Mouse CD27, also known as TNFRSF7, is a member of the tumor necrosis factor receptor (TNFR) superfamily characterized by the presence of a Cys-knot motif in the extracellular region, which occurs three times in CD27. CD27 is a type I transmembrane glycoprotein existing as disulfide-linked homodimer, and has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis. CD27 has been defined as a T and B cell co-stimulatory molecule, and its activity is governed by the transient availability of its TNF-like ligand CD70 on lymphocytes and dendritic cells. In man and mouse, CD27 is restricted to lymphoid cells and present on the great majority of naive CD4+ and CD8+ T cells.
Source : Human Cells.
Molecular Mass : The recombinant mouse CD27/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 410 amino acids and has a predicted molecular mass of 46.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm CD27/Fc monomer is approximately 60-65 kDa due to glycosylation.
Predicted N Terminal : Thr 21.
Purity : > 94 % as determined by SDS-PAGE.
Formulation : Lyophilized from sterile PBS , pH 7.4.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Storage And Stability : Samples are stable for up to twelve months from date of receipt at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : Cd27 CD27 antigen [ Mus musculus ]
Synonyms : Cd27; CD27 antigen; S152; Tp55; Tnfrsf7; CD27 antigen; CD antigen 27; CD27L receptor; OTTMUSP00000029268; OTTMUSP00000029269; OTTMUSP00000029270; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Gene ID : 21940
mRNA Refseq : NM_001033126
Protein Refseq : NP_001028298
UniProt ID : P41272
Chromosome Location : 6 F3; 6 60.35 cM
Pathway : Cytokine-cytokine receptor interaction
Function : protein binding; receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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