Recombinant Human CARD14, T7-tagged

• Cat.No.: CARD14-3041H
• Product Overview: Recombinant Human CARD14 was produced inE.coliwith a T7 tag at N-terminus. MW = 113300 Da (1-434 aa).

Specification

• Cat. No.: CARD14-3041H
• Description: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-κB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
• Source: E.coli.
• Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
• Purity: 95%.
• Applications: MS. SDS.

Gene Information

• Gene Name: CARD14 caspase recruitment domain family, member 14 [ Homo sapiens ]
• Synonyms: CARD14; caspase recruitment domain family, member 14; BIMP2; CARMA2; caspase recruitment domain-containing protein 14; carma 2; card-maguk protein 2; CARD-containing MAGUK 2 protein; CARD-containing MAGUK protein 2; bcl10-interacting maguk protein 2; Carma 2
• Gene ID: 79092
• mRNA Refseq: NM_024110
• Protein Refseq: NP_077015
• MIM: 607211
• UniProt ID: Q9BXL6
• Chromosome Location: 17q25
• Function: CARD domain binding; protein binding