Cat. No. : |
CALN1-2869H |
Product Overview : |
Recombinant human CALN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Description : |
CALN1 is high similarity to the calcium-binding proteins of the calmodulin family. This protein contains two EF-hand domains and potential calcium-binding sites. Also, Itnegatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CALN1 play a role in the physiology of neurons and is potentially important in memory and learning. |
Source : |
E.coli. |
Sequence : |
MGSSHHHHHH SSGLVPRGSH MPFHHVTAGL LYKGNYLNRS LSAGSDSEQL ANISVEELDE IREAFRVLDR DGNGFISKQE LGMAMRSLGY MPSEVELAII MQRLDMDGDG QVDFDEFMTI LGPKLVSSEG RDGFLGNTID SIFWQFDMQR ITLEELKHIL YHAFRDHLTM KDIENIIINE EESLNETSGN CQTEFEGVHS QKQNRQTCVR KS. |
Purity : |
> 90% by SDS – PAGE. |
MW : |
24.0 kDa (212aa) confirmed by MALDI-TOF. |
Form : |
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl, 0.1mM PMSF. |
Concentration : |
0.5mg/ml (determined by Bradford assay). |
Storage : |
Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |