| Cat. No. : | CALN1-2869H |
| Product Overview : | Recombinant human CALN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Description : | CALN1 is high similarity to the calcium-binding proteins of the calmodulin family. This protein contains two EF-hand domains and potential calcium-binding sites. Also, Itnegatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CALN1 play a role in the physiology of neurons and is potentially important in memory and learning. |
| Source : | E.coli. |
| Sequence : | MGSSHHHHHH SSGLVPRGSH MPFHHVTAGL LYKGNYLNRS LSAGSDSEQL ANISVEELDE IREAFRVLDR DGNGFISKQE LGMAMRSLGY MPSEVELAII MQRLDMDGDG QVDFDEFMTI LGPKLVSSEG RDGFLGNTID SIFWQFDMQR ITLEELKHIL YHAFRDHLTM KDIENIIINE EESLNETSGN CQTEFEGVHS QKQNRQTCVR KS. |
| Purity : | > 90% by SDS – PAGE. |
| MW : | 24.0 kDa (212aa) confirmed by MALDI-TOF. |
| Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl, 0.1mM PMSF. |
| Concentration : | 0.5mg/ml (determined by Bradford assay). |
| Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Gene Name : | CALN1 calneuron 1 [ Homo sapiens ] |
| Synonyms : | CALN1; calneuron 1; OTTHUMP00000160216; OTTHUMP00000198477; OTTHUMP00000198493; OTTHUMP00000210382; OTTHUMP00000210383; calcium-binding protein 8; calcium-binding protein CABP8; calneuron I; calneuron-; CABP8; CALN1 |
| Gene ID : | 83698 |
| mRNA Refseq : | NM_001017440 |
| Protein Refseq : | NP_001017440 |
| MIM : | 607176 |
| UniProt ID : | Q9BXU9 |
| Chromosome Location : | 7q11 |
| Function : | calcium ion binding |
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