"CBR4" Related Products

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Recombinant Human CBR4, His-tagged

Cat. No. : CBR4-2876H
Product Overview : Recombinant human CBR4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description : CBR4 belongs to the short-chain dehydrogenase/reductase family. The formation of heteroteramer with HSD17B8 has NADH-dependent3-ketoacyl-acyl carrier protein reductase activity for o- and p-quinones. It plays a role in biosynthesis of fatty acids in mitochondria and has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
Source : E.coli.
Sequence : MGSSHHHHHH SSGLVPRGSH MDKVCAVFGG SRGIGRAVAQ LMARKGYRLA VIARNLEGAK AAAGDLGGDH LAFSCDVAKE HDVQNTFEEM EKHLGRVNFL VNAAGINRDG LLVRTKTEDM VSQLHTNLLG SMLTCKAAMR TMIQQQGGSI VNVGSIVGLK GNSGQSVYSA SKGGLVGFSR ALAKEVARKK IRVNVVAPGF VHTDMTKDLK EEHLKKNIPL GRFGETIEVA HAVVFLLESP YITGHVLVVD GGLQLIL.
Purity : > 95% by SDS – PAGE.
MW : 27.5kDa (257aa) confirmed by MALDI-TOF.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 5mM DTT, 200mM NaCl.
Concentration : 0.5mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : CBR4 carbonyl reductase 4 [ Homo sapiens ]
Synonyms : CBR4; carbonyl reductase 4; FLJ14431, SDR45C1; 3-oxoacyl-[acyl-carrier-protein] reductase; OTTHUMP00000219599; OTTHUMP00000219638; carbonic reductase 4; carbonyl reductase family member 4; quinone reductase CBR4; short chain dehydrogenase/reductase family 45C, member 1
Gene ID : 84869
mRNA Refseq : NM_032783
Protein Refseq : NP_116172
UniProt ID : Q8N4T
Chromosome Location : 4q32.3
Function : NADPH binding; NADPH dehydrogenase (quinone) activity; protein binding; quinone binding

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