"Tnfsf11" Related Products


Recombinant Rat Tnfsf11

Cat. No. : Tnfsf11-2680R
Product Overview : Recombinant rat Tnfsf11 is a 19.4 kDa polypeptide comprising the TNF homologous region of RANKL (174 amino acid residues). It is expressed inE. coli.
Description : RANKL (Receptor Activator for Nuclear Factor κ B Ligand), also known as TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and ODF (osteoclast differentiation factor), is a molecule important in bone metabolism. This natural and necessary surface-bound molecule found on osteoblasts serves to activate osteoclasts, which are the cells involved in bone resorption. Overproduction of RANKL is implicated in a variety of degenerative bone diseases, such as rheumatoid arthritis and psoriatic arthritis.
Source : E. coli.
Purity : Greater than 98% (determined by SDS-PAGE and HPLC analysis).
MW : 19.4 kDa.
Endotoxin Level : < 0.1 ng per μg of rHu APO-E4 (1EU/μg).
Formulation : Lyophilized from a sterile-filtered solution with no additives.
Reconstitution : Please Note: Always centrifuge product before opening vial. The lyophilized protein should be reconstituted with distilled, sterile water to a concentration of 0.1-1.0 mg/ml. For further dilution, carrier protein (0.1% BSA or HSA) should be added to avoid loss of bioactivity.
Storage : The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.
Gene Name : Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 [ Rattus norvegicus ]
Synonyms :
Tnfsf11; tumor necrosis factor (ligand) superfamily, member 11; ODF; OPGL; TNF-related activation-induced cytokine; TRANCE; osteoclast differentiation factor; osteoprotegerin ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; tumor necrosis factor ligand superfamily member 11; RANKL
Gene ID : 117516
mRNA Refseq : NM_057149
Protein Refseq : NP_476490
UniProt ID : Q9ESE2
Chromosome Location : 15q11
Pathway : Cytokine-cytokine receptor interaction
Function : cytokine activity; protein binding; tumor necrosis factor receptor binding; receptor activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.