HAT (H4) Activity Fluorometric Assay Kit
Cat.No. : | Kit-2262 |
Product Overview : | Histone Acetyltransferases (HATs) are enzymes that acetylate histone substrates resulting in important regulatory effects on chromatin structure and assembly, and gene transcription. Modifications of these proteins by HATs play an important role in the control of gene expression, and their dysregulation has been linked to cancer, neurodegeneration, and other diseases. HAT Activity Assay Kit utilizes Acetyl CoA and H4 histone peptide as substrates. In this assay, HAT enzyme catalyzes the transfer of acetyl groups from Acetyl-CoA to the histone peptide, thereby generating two products - acetylated peptide and CoA-SH. The CoA-SH reacts with the developer and to generate a product that is detected fluorometrically at Ex/Em = 535/587 nm. The assay can detect HAT activity equivalent to as low as 1.5 μU of p300 in a variety of samples. |
- Specification
- Gene Information
- Related Products
Applications : | Measurement of HAT activity of immunoprecipitated samples. Measurement of HAT activity of purified enzyme preparations. Measurement of HAT activity in Nuclear Extracts. |
Storage : | -80°C |
Size : | 100 assays |
Products Types
◆ Assay kits | ||
Kit-0410 | Histone Acetyltransferase Activity Colorimetric Assay Kit | +Inquiry |
Kit-0408 | HAT Activity Fluorometric Assay Kit | +Inquiry |
Kit-0411 | Histone Acetyltransferase Inhibitor Screening Assay Kit | +Inquiry |
Kit-0409 | HAT Inhibitor Screening Assay Kit | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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