Human Interferon alpha-2a (rDNA derived) Reference standard

• Cat.No.: INFA2a-152H
• Product Overview: This material is intended for use as the primary biological reference standard in bioassays for IFN-alpha 2a.

Specification

• Species: Human
• Enzyme Unit: 63, 000 International Units per ampoule.
• Usage: No attempt should be made to weigh out any portion of the freeze-dried material prior to reconstitution. No attempt should be made to weigh out any portion of the freeze-dried material. Dissolve the total contents of the ampoule in 0.5ml of sterile distilled water and transfer to a sterile container. Rinse the ampoule with about 0.4ml of sterile distilled water and add to the first solution. Make up the total volume to 1.0ml with sterile distilled water. The final solution will contain IFN alpha 2a at a concentration of 63000 International Units per ml. Use carrier protein where dilution is required.
• Notes: This preparation is not for administration to humans. The preparation contains material of human origin, and either the final product or the source materials, from which it is derived, have been tested and found negative for HBsAg, anti-HIV and HCV RNA. As with all materials of biological origin, this preparation should be regarded as potentially hazardous to health. It should be used and discarded according to your own laboratorys safety procedures. Such safety procedures should include the wearing of protective gloves and avoiding the generation of aerosols. Care should be exercised in opening ampoules or vials, to avoid cuts.
• Stability: Reference materials are held at Creative Biomart within assured, temperature- controlled storage facilities and they should be stored on receipt as indicated on the label. Accelerated degradation studies have indicated that this material is suitably stable, when stored at -20°C or below, for the assigned values to remain valid until the material is withdrawn or replaced. These studies have also shown that the material is suitably stable for shipment at ambient temperature without any effect on the assigned values. Once reconstituted, diluted or aliquoted, users should determine the stability of the material according to their own method of preparation, storage and use. Users who have data supporting any deterioration in the characteristics of any reference preparation are encouraged to contact Creative Biomart.
• Storage: For economy of use, it is recommended that the final solution be sub- divided into several small aliquots and stored at -40°C or below. Avoid repeated thawing/freezing. Unopened ampoules should be stored at – 20°C. Please note: because of the inherent stability of lyophilized material, Creative Biomart may ship these materials at ambient temperature.

Gene Information

• Gene Name: IFNA2 interferon, alpha 2 [ Homo sapiens ];
• Official Symbol: IFNA2
• Synonyms: IFNA; INFA2; IFNA2B; IFN-alphaA; interferon alpha-2; leIF A; IFN-alpha-2; interferon alpha A; alpha-2a interferon; interferon alpha 2a; interferon alpha 2b
• Gene ID: 3440
• mRNA Refseq: NM_000605
• Protein Refseq: NP_000596
• MIM: 147562
• UniProt ID: P01563
• Chromosome Location: 9p22
• Pathway: Autoimmune thyroid disease, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hepatitis C, conserved biosystem
• Function: cytokine activity; protein binding; type I interferon receptor binding

Reviews

01/23/2019

Gel electrophoresis consistently displayed well-defined bands, affirming the product's purity and reliability.

03/30/2018

Precise immunoprecipitation results consistently reflected the product's quality.

10/26/2016

The product's inclusion consistently led to a significant upregulation of target protein expression levels.

Q&As

How does INF2A protein impact actin cytoskeleton remodeling?

INF2A protein is involved in actin cytoskeleton remodeling, regulating cell shape and motility.

How does INF2A protein’s role relate to cellular protrusion formation?

INF2A protein’s involvement can lead to the formation of cellular protrusions, affecting cell morphology.

How is INF2A protein’s involvement studied in actin dynamics?

Research investigates how INF2A protein’s role affects actin dynamics and cellular responses.

Where is INF2A protein predominantly located within cells?

INF2A protein is primarily localized within specific cellular compartments, such as the cytoskeleton.

Can INF2A protein’s function influence cellular responses to mechanical forces?

Yes, INF2A protein’s function can modulate cellular responses to mechanical stresses and forces.

Can INF2A protein’s function impact cellular responses to mechanical stresses?

Yes, INF2A protein’s function could modulate how cells respond to mechanical stresses and maintain stability.

What is the unique role of INF2A protein in cellular processes?

INF2A protein serves a specialized function that contributes to distinct cellular processes.