Mouse Anti-FGF2 Monoclonal Antibody

• Cat.No.: DMABT-H18566
• Product Overview: Mouse Anti-FGF2 Monoclonal Antibody

Specification

• Species: Human
• Source: Mouse
• Tag: Non
• Antigen Description: Fibroblast growth factor-basic (FGF-b, FGF-2) is a heparin-binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. FGF-basic also exerts a potent angiogenic activity in vivo. FGF-basic has been isolated from neural, pituitary, adrenal cortex, and placental tissues.
• Target: FGF2
• Immunogen: Recombinant human bFGF
• Isotype: IgG1, kappa
• species: Human
• Clone: KLGc-3
• Conjugation: Biotin
• Applications: ELISA,ELISPOT
• Preparation: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
• Usage recommendation: Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 1-4 μg/ml is recommended. To obtain a linear standard curve, serial dilutions of human FGF-basic protein ranging from 4000 to 30 pg/ml are recommended for each ELISA plate.It is recommended that the reagent be titrated for optimal performance for each application.
• Concentration: 0.5 mg/ml
• Storage: The antibody solution should be stored undiluted at 4 °C.Do not freeze.
• Size: 500 μg

Gene Information

• Gene Name: FGF2 fibroblast growth factor 2 (basic) [ Homo sapiens ]
• Official Symbol: FGF2
• Synonyms: FGF2; fibroblast growth factor 2 (basic); FGFB; fibroblast growth factor 2; prostatropin; heparin-binding growth factor 2; basic fibroblast growth factor bFGF; BFGF; FGF-2; HBGF-2
• Gene ID: 2247
• mRNA Refseq: NM_002006
• Protein Refseq: NP_001997
• MIM: 134920
• UniProt ID: P09038
• Chromosome Location: 4q26
• Pathway: Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1b ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem
• Function: chemoattractant activity; cytokine activity; fibroblast growth factor binding; fibroblast growth factor receptor binding; growth factor activity; heparin binding; ligand-dependent nuclear receptor transcription coactivator activity; protein binding; protein tyrosine kinase activity; voltage-gated calcium channel activity