Mouse Anti-TREM1 Monoclonal Antibody

Name: Mouse Anti-TREM1 Monoclonal Antibody
SKU: DMABT-H18611

Specification
Gene Information
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Species :	Human
Source :	Mouse
Tag :	Non
Antigen Description :	TREM-1 is a 30 kD glycoprotein also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. It is a Type I membrane protein that contains an immunoglobulin-like V-type domain. Alternatively spliced protein variant may be secreted. TREM-1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes); TREM-1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM-1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM-1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock.
Target :	TREM1
Immunogen :	Recombinant human TREM-1
Isotype :	IgG2b, kappa
species :	Human
Conjugation :	N/A
Applications :	ELISA,WB,Flow Cyt
Preparation :	The antibody was purified by affinity chromatography.
Usage recommendation :	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.5 μg per million cells in 100 μl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Concentration :	0.5 mg/ml
Storage :	The antibody solution should be stored undiluted at 4 °C.
Size :	25 μg;100 μg

Gene Name	TREM1 triggering receptor expressed on myeloid cells2[ Homo sapiens ]
Official Symbol	TREM1
Synonyms	TREM1; triggering receptor expressed on myeloid cells 1; CD354; TREM 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1; TREM-1;
Gene ID	54210
mRNA Refseq	NM_001242589
Protein Refseq	NP_001229518
MIM	605085
UniProt ID	Q9NP99
Chromosome Location	6p21.1
Pathway	Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem;
Function	receptor activity;