| Background : |
Cytomegalovirus (CMV, or human betaherpesvirus 5) is a human-specific double-stranded DNA virus, belonging to the Herpesviridae family. CMV is ubiquitous and CMV infection is globally widespread. The virus is transmitted through direct contact with infected bodily fluids, or though contact with virus-infected transplant and transfusion material. Presently, CMV infection is mostly controlled in immune compromised patients by available antiviral drugs, yet it continues to maintain its role as one of the most dangerous infectious agents for an unborn infant. Primary infection is consistently associated with the presence of a virus specific IgM antibody response. Use of Cytomegalovirus purified antigen will aid in improving serology based assays for early detection. |
| Purity : |
Purified by ultracentrifugation |
| Inactivation : |
Purified virus particles were lysed in 0.2% Triton X-100 in STE buffer. The lysate was tested by passage on permissive cells for 2 weeks yielding no CPE. |
| Formulation : |
0.2% Triton X-100, 10mM Tris-HCl, 1mM EDTA and 100mM NaCl, pH7.8 |
| Storage : |
Store frozen at less than -20 centigrade, preferably -80 centigrade. |
| Concentration : |
Adjusted to 1 mg/mL by BCA assay |
| Notes : |
This product is intended for research and manufacturing uses only. It is not a diagnostic device. The user assumes all responsibility for care, custody and control of the material, including its disposal, in accordance with all regulations. |
| Type : |
Native |
| ClassID 1 : |
Infectious Disease |
