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Native Human ALB therapeutic protein (Albumin iodinated I-131 serum)

Cat.No. : ALB-P042H
Product Overview : A diagnostic radiopharmaceutical containing iodinated I 131 albumin for intravenous imaging. Following intravenous injection, radioiodinated albumin human is uniformly distributed throughout the intravascular pool within 10 minutes; extravascular distribution takes place more slowly (2 days). Indicated for use in determinations of total blood and plasma volumes, cardiac output, cardiac and pulmonary blood volumes and circulation times
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Description : Regulates the colloidal osmotic pressure of blood. It is used to increase the circulating plasma volume, thereby reducing hemoconcentrtion and blood viscosity. Also used as a transport protein that binds naturally occurring, therapeutic and toxic materials in circulation.
Species : Human
Molecular Mass : 66.5 kDa
AA Sequence : MKWVTFISLLFLFSSAYSRGVFRRD AHKSEVAHRFKDLGEENFKALVLIA FAQYLQQCPFEDHVKLVNEVT EFAKTCVADESAENCDKSLHTLFGD KLCTVATLRETYGEMADCCAKQEPE RNECFLQHKDDNPNLPRLVRP EVDVMCTAFHDNEETFLKKYLYEIA RRHPYFYAPELLFFAKRYKAAFTEC CQAADKAACLLPKLDELRDEG KASSAKQGLKCASLQKFGERAFKAW AVARLSQRFPKAEFAEVSKLVTDLT KVHTECCHGDLLECADDRADL AKYICENQDSISSKLKECCEKPLLE KSHCIAEVENDEMPADLPSLAADFV GSKDVCKNYAEAKDVFLGMFL YEYARRHPDYSVVLLLRLAKTYETT LEKCCAAADPHECYAKVFDEFKPLV EEPQNLIKQNCELFEQL GEYKFQNALLVRYTKKVPQVSTPTL VEVSRNLGKVGSKCCKHPEAKRMPC AEDCLSVFLNQLCVLHEKTPV SDRVTKCCTESLVNGRPCFSALEVD ETYVPKEFNAETFTFHADICTLSEK ERQIKKQTALVELVKHKPKAT KEQLKAVMDDFAAFVEKCCKADDKE TCFAEEGKKLV
Endotoxin : < 0.1 EU per μg of the protein
Purity : >95%
Tag : Non
Alias : ALB; PRO0883; PRO0903; Albumin iodinated I-131 serum
Gene Name : ALB albumin [ Homo sapiens ]
Official Symbol : ALB
Synonyms : ALB; albumin; serum albumin; albumin (32 AA); albumin (AA 34); growth-inhibiting protein 20; cell growth inhibiting protein 42; PRO0883; PRO0903; PRO1341; DKFZp779N1935;
Gene ID : 213
mRNA Refseq : NM_000477
Protein Refseq : NP_000468
UniProt ID : P02768
Chromosome Location : 4q13.3
Pathway : Bile acid and bile salt metabolism, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Hemostasis, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function : DNA binding; antioxidant activity; cell surface binding; chaperone binding; copper ion binding; drug binding; drug binding; enzyme binding; fatty acid binding; fatty acid binding; metal ion binding; contributes_to oxygen binding; protein binding; pyridoxal phosphate binding; toxin binding; zinc ion binding;

Not For Human Consumption!

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Customer Reviews (4)

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Reviews
12/26/2022

    I am genuinely excited to embark on this scientific journey, empowered by the superior ALB protein and the manufacturer's unwavering commitment to ensuring my success.

    09/13/2022

      By utilizing the ALB protein, I can approach my research with unwavering confidence in its quality, along with the unparalleled support provided by its manufacturer.

      07/10/2022

        The ALB protein offers exceptional quality that seamlessly aligns with my experimental requirements.

        03/10/2017

          Their expertise and prompt responsiveness exemplify their dedication to providing customers with solutions and guidance.

          Q&As (17)

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          Can ALB protein levels be used to monitor response to treatment or progression of certain diseases? 03/20/2023

          Yes, ALB protein levels can be used as a marker to monitor the response to treatment or progression of certain diseases. For instance, in liver diseases, ALB protein levels can be monitored to assess the effectiveness of treatment or progression of liver damage. Similarly, in diseases like nephrotic syndrome, monitoring ALB protein levels can help evaluate the response to therapy and disease progression. However, it is crucial to interpret ALB protein levels in conjunction with other clinical parameters and in consultation with a healthcare provider.

          Does ALB protein have any clinical significance beyond its role in transport and fluid balance? 09/15/2022

          Yes, ALB protein has clinical significance beyond its basic functions. It has been associated with various health conditions and can serve as a prognostic marker. For example, low ALB protein levels have been linked to increased mortality risk in hospitalized patients and have been used as a prognostic marker for chronic diseases like heart failure and cancer. High ALB protein levels have also been associated with better outcomes in certain health conditions, such as in patients with traumatic brain injury.

          Are there factors other than medical conditions that can affect ALB protein levels? 01/24/2022

          Yes, several factors other than medical conditions can affect ALB protein levels. Age is one such factor, as ALB protein levels tend to decrease slightly with advancing age. Gender can also play a role, with studies suggesting that males may have slightly higher ALB protein levels compared to females. Additionally, certain lifestyle factors like smoking and excessive alcohol consumption have been associated with lower ALB protein levels. It is important to consider these factors when interpreting ALB protein levels in an individual.

          How can low ALB protein levels be treated? 11/10/2020

          The treatment of low ALB protein levels depends on the underlying cause. In cases of liver disease, treating the liver condition can help improve ALB protein levels. This may include lifestyle modifications, medication, or, in severe cases, liver transplantation. In instances of malnutrition or inadequate dietary intake, improving nutrition and incorporating protein-rich foods can help increase ALB protein levels.

          Can ALB protein levels be used as a screening tool for liver disease? 11/17/2019

          ALB protein levels can be used as part of a comprehensive assessment for liver disease but are not usually used as a stand-alone screening tool. Liver function tests, which may include measuring ALB protein levels, as well as other markers like liver enzymes and bilirubin levels, can help evaluate liver health. However, a proper diagnosis of liver disease typically requires a combination of clinical evaluation, medical history, imaging studies, and additional laboratory tests.

          Are there specific diseases or conditions where monitoring ALB protein levels is important? 09/16/2019

          Monitoring ALB protein levels is important in various diseases and conditions, particularly those involving liver or kidney dysfunction, malnutrition, inflammatory disorders, and conditions associated with protein loss or inflammation.

          Are there any specific medical conditions that can affect ALB protein levels? 07/10/2019

          Yes, several medical conditions can affect ALB protein levels. Liver diseases, including cirrhosis, hepatitis, and liver failure, can lead to decreased ALB protein production. Kidney diseases, such as nephrotic syndrome or chronic kidney disease, can cause ALB protein loss through the urine. Inflammatory conditions like rheumatoid arthritis or systemic lupus erythematosus can also affect ALB protein levels. Additionally, malnutrition and certain cancers can contribute to low ALB protein levels.

          How is ALB protein measured in the body? 04/17/2019

          The level of ALB protein in the body can be measured through a blood test called serum albumin test. This test measures the concentration of ALB protein in the blood and is commonly used to assess liver function and nutritional status.

          Are there any specific dietary recommendations to maintain ALB protein levels? 03/24/2019

          Eating a balanced diet that includes an adequate amount of protein can help maintain ALB protein levels. Good sources of protein include lean meats, poultry, fish, eggs, dairy products, legumes, and nuts. However, it is always advisable to consult with a healthcare professional or registered dietitian for personalized dietary recommendations based on individual needs and underlying health conditions.

          Can ALB protein levels fluctuate throughout the day? 03/22/2019

          ALB protein levels generally remain relatively stable throughout the day. However, it is worth noting that certain factors, such as hydration status, can influence ALB levels. For example, dehydration can lead to a temporary increase in ALB concentration, while overhydration can lead to a temporary decrease. It is essential to consider the overall clinical context and interpret ALB protein levels in conjunction with other relevant clinical information.

          What can low ALB protein levels indicate? 02/27/2019

          Low ALB protein levels, also known as hypoalbuminemia, can indicate several underlying health conditions. It is commonly associated with liver diseases, such as cirrhosis, hepatitis, and liver failure. Other causes of low ALB protein levels include malnutrition, kidney disease, severe burns, inflammatory bowel disease, and certain types of cancer.

          Are high ALB protein levels ever a cause for concern? 08/30/2018

          While low ALB protein levels are more commonly associated with health concerns, high ALB protein levels can also be a cause for concern in certain situations. Elevated ALB protein levels can occur in conditions such as dehydration, severe burns, and certain types of cancer. Additionally, high ALB protein levels can sometimes be an indicator of an underlying inflammatory process. It is important to consider the individual's overall clinical context and consult with a healthcare professional for proper evaluation and interpretation of elevated ALB protein levels.

          Can ALB protein levels change during pregnancy? 06/12/2018

          Yes, ALB protein levels can decrease slightly during pregnancy. This is considered a normal physiological change, and the decrease in ALB protein levels is believed to be due to increased blood volume and fluid retention. However, significant or persistent decreases in ALB protein levels during pregnancy may require further evaluation.

          Can ALB protein levels be influenced by genetic factors? 04/20/2018

          Yes, genetic factors can influence ALB protein levels. Variations in genes involved in ALB protein synthesis or metabolism can contribute to differences in ALB protein levels among individuals. These genetic factors can be inherited and may affect an individual's baseline ALB protein levels. However, genetic factors alone may not account for significant changes in ALB protein levels, and additional factors like medical conditions, medications, and environmental factors should also be considered.

          Can ALB protein levels be used to assess nutritional status? 11/09/2016

          Yes, ALB protein levels are often used as an indicator of nutritional status. Since ALB protein is primarily synthesized by the liver and its production can be affected by nutrient deficiencies or malnutrition, low levels can suggest poor nutritional status. However, it is important to note that ALB protein levels can be influenced by various factors, and additional measurements and assessments may be needed to comprehensively evaluate nutritional status.

          Are there any medications that can affect ALB protein levels? 10/26/2016

          Yes, certain medications can affect ALB protein levels. Some medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and some antiepileptic medications, have been reported to potentially decrease ALB protein levels. However, it is essential to consult with a healthcare professional or pharmacist to understand the potential effects of specific medications on ALB protein levels.

          Can high ALB protein levels be a concern? 05/11/2016

          High ALB protein levels, known as hyperalbuminemia, are less common than low levels and are usually not a cause for concern on their own. In some instances, high ALB protein levels can be seen in dehydration or certain medical conditions like severe burns or chronic inflammation. It is important to assess the underlying cause if hyperalbuminemia is observed in order to address any potential health issues.

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