Native Human Oxytocin, Prepropeptide

• Cat.No.: OXT-5360H
• Product Overview: Native human OXT is synthetic.

Specification

• Species: Human
• Source: Synthetic
• Tag: Non
• Description: HumanOXT (Pitocin/Syntocinon) stimulates uterine smooth muscle contractions indirectlyand stimulates the mammary glands to increase lactation without increasingthe production of milk.
• Form: Lyophilized from aconcentrated (1 mg/ml) solution in water containing no additives.
• Appearance: Sterile FilteredWhite lyophilized (freeze-dried) powder.
• Sequence: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2.
• Purity: Greater than 98.0%as determined by: Analysis by RP-HPLC and Mass Spectral Analysis (MALDI-TOFexhibits correct MW).
• Storage: Lyophilized Oxytocinalthough stable at room temperature for 3 weeks, should be stored desiccatedbelow -18°C. Upon reconstitution Oxytocin should be stored at 4°C between 2-7days and for future use below -18°C. For long term storage it is recommendedto add a carrier protein (0.1% HSA or BSA). Avoid freeze-thaw cycles.
• Pathways: Class A/1(Rhodopsin-like receptors); G alpha (q) signalling events; GPCR downstreamsignaling; Myometrial Relaxation and Contraction Pathways; Peptideligand-binding receptors; Signal Transduction; Signaling by GPCR;Vasopressin-like receptors

Gene Information

• Gene Name: OXT oxytocin, prepropeptide [ Homosapiens ]
• Official Symbol: OXT
• Synonyms: OXT; oxytocin, prepropeptide;OT; OT-NPI; MGC126890; MGC126892; oxytocin-neurophysin 1; neurophysin I;OTTHUMP00000030079; oxytocin, prepro- (neurophysin I); oxytocin-neurophysinI, preproprotein
• Gene ID: 5020
• mRNA Refseq: NM_000915
• Protein Refseq: NP_000906
• MIM: 167050
• UniProt ID: P01178
• Chromosome Location: 20p13
• Function: neurohypophysealhormone activity; oxytocin receptor binding