Native Human Serpin Peptidase Inhibitor, Clade A (alpha-1 antiproteinase, antitrypsin), Member 3
Cat.No. : | SERPINA3-5331H |
Product Overview : | Native human SERPINA3 expressed by Human Plasma |
- Specification
- Gene Information
- Related Products
Description : | SERPINA3is an alpha globulin glycoprotein that is a member of the serine proteinaseinhibitor (serpin) family. It inhibits the activity of certain proteinases,such as cathepsin G that are found in neutrophils, and chymases found in mastcells. This activity protects some tissues, such as the lower respiratorytract, from damage caused by proteolytic enzymes. SERPINA3 is produced in theliver, and is an acute phase protein that is induced during inflammationfound at concentrations of 45 mg/100 ml. Clinically, it is elevated ininflammatory conditions, some malignancies, Crohn"s disease, ulcerativecolitis, and burn injuries. |
Source : | human plasma |
Species : | Human |
Form : | Lyophilized from 20mM Tris-HCl pH 7.4 + 150 mM NaCl. |
Purity : | >95% by SDS-PAGE. |
Storage : | Store at -70°C . |
Gene Name : | SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 [ Homo sapiens ] |
Official Symbol : | SERPINA3 |
Synonyms : | SERPINA3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; AACT, alpha 1 antichymotrypsin , serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 3; alpha-1-antichymotrypsin; |
Gene ID : | 12 |
mRNA Refseq : | NM_001085 |
Protein Refseq : | NP_001076 |
MIM : | 107280 |
UniProt ID : | P01011 |
Chromosome Location : | 14q32.1 |
Pathway : | Selenium Pathway, organism-specific biosystem; |
Function : | DNA binding; peptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; |
Products Types
◆ Recombinant Protein | ||
SERPINA3-2H | Recombinant Horse SERPINA3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SERPINA3-571H | Recombinant Human SERPINA3 Protein, His-tagged | +Inquiry |
SERPINA3-5611H | Recombinant Human SERPINA3 Protein (Lys235-Arg394), N-GST tagged | +Inquiry |
SERPINA3-2700H | Active Recombinant Human SERPINA3 protein, His-tagged | +Inquiry |
SERPINA3-3238H | Recombinant Human SERPINA3 protein, His-tagged | +Inquiry |
◆ Native Protein | ||
SERPINA3-8349H | Native Human SERPINA3 | +Inquiry |
SERPINA3-27285TH | Native Human SERPINA3 | +Inquiry |
SERPINA3-8008H | Native Human Serum Alpha 1-AntiChymoTrypsin | +Inquiry |
◆ Lysates | ||
SERPINA3-2522HCL | Recombinant Human SERPINA3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket