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Native Jackbean Concanavalin A Lectin (Con A), TRITC-Conjugated

Cat.No. : Con A-485J
Product Overview : Native Jackbean Concanavalin A Lectin (Con A) - TRITC (Rhodamine)
Blood Group Specificity: Non-specific
Preferred Sugar Specificity: α-Mannose, α-Glucose
Inhibiting or Eluting Sugar: α-Methylmannoside + α-Methylglucoside
Divalent Ions: Ca++, Mn++
Excitation: 545-555 nm
Emission: 570-580 nm
Mitogenic Activity: Yes
Hazardous Shipping: Non-hazardous
Fluorescence: Orange
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Description : Affinity purified concanavalin A (Con A) is composed of two identical subunits of 237 amino acid residues (MW: 26,000 without any cystine residues). Con A does not have a blood group specificity. It exhibits mitogenic activity with lymphocytes and cancer cells. While lymphocytes and cancer aggregate by Con A; normal white cells do not. Normal cells react to Con A after proteolytic treatment which suggests that trypsinization causes clustering of the reactive glycan residues on the membrane. Con A interacts with cell types include locust muscle fibers, adipocytes, and rat liver plasma membrane components. This lectin induces endoreduplication in mammalian cells and it reacts with E. coli, Dictyostelium discoideum and Bacillus lipopolysaccharides. Immobilized Con A has been used in affinity chromatography purifications of a wide variety of glycoproteins and cellular structures. Concanavalin A (Jackbean) Lectin (Con A) is labeled with tetramethylrhodamine isothiocyanate (TRITC) and has an appropriate number of fluorochromes bound to provide the optimum staining characteristics for this lectin. TRITC is a bright orange or red-fluorescent dye with excitation ideally suited to the 532-nm laser line. TRITC labeled Con A can be used for cellular imaging applications.
Source : Jackbean
Species : Jackbean
Form : Liquid
Purity : High Purity Grade
Stability : Shelf Life: 1 year
Storage : At 2-8 centigrade.
Concentration : 5 mg/mL
Official Symbol : Con A
Synonyms : Concanavalin A Lectin; Con A
Official Symbol : Con A
Synonyms : Concanavalin A Lectin; Con A

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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