Native Mushroom Agaricus bisporus Lectin (ABA/ABL)

• Cat.No.: ABA/ABL-579M
• Product Overview: Native Mushroom Agaricus bisporus Lectin (ABA/ABL) - Pure
  Blood Group Specificity: Non-specific
  Preferred Sugar Specificity: Galactoseβ1-3N-Acetylgalactosamine
  Inhibiting or Eluting Sugar: Fetuin
  Divalent Ions: None Required
  Mitogenic Activity: No
  Hazardous Shipping: Non-hazardous
  Appearance Color: White to off-white

Specification

• Species: Mushroom
• Source: Mushroom
• Description: Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-β-1,3-N-acetylgalactosamine and another for galactose-β-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.
• Form: Lyophilized Powder
• Molecular Mass: 58.5 kDa
• Purity: Affinity purified
• Applications: Cancer biomarker, Glycobiology, IHC, Inhibits proliferation of malignant cells without cytotoxicity, Binds sialylated and non-sialylated T antigen
• Stability: Shelf Life: 2 years
• Storage: At -20 centigrade.

Gene Information

• Official Symbol: ABA/ABL
• Synonyms: Agaricus bisporus Lectin; ABA/ABL