Native Rat Serpin Peptidase Inhibitor, Clade C (antithrombin), Member 1

Species :	Rat
Source :	Rat Plasma
Tag :	Non
Description :	Serpinc1 is a smallprotein that inactivates several enzymes of the Coagulation Cascade. Serpinc1is a glycoprotein produced by the liver and consists of 432aa. It containsthree disulfide bonds and a total of four possible glycosylation sites. AT3includes two functional domains:the heparin binding-domain at the N-terminusof the mature protein, and the reactive site domain at the C-terminus. The inhibitoryactivity is enhanced by the presence of heparin.
Form :	Frozen Liquid in0.05 M Sodium Phosphate+0.1 M NaCl+1 mM EDTA pH 7.4.
Purity :	Severalchromatographic steps.
Storage :	Store at -70°C.
Concentration :	5.0 mg/mL.

Gene Name	Serpinc1 serpin peptidase inhibitor, clade C (antithrombin), member 1 [ Rattus norvegicus ]
Official Symbol	Serpinc1
Synonyms	SERPINC1; serpin peptidase inhibitor, clade C (antithrombin), member 1; antithrombin-III; antithrombin III; serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), memb
Gene ID	304917
mRNA Refseq	NM_001012027
Protein Refseq	NP_001012027
Pathway	Common Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem;
Function	heparin binding; protease binding; protease binding; protein binding; serine-type endopeptidase inhibitor activity;